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Auristatin E

Cat. No. M9818

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Auristatin E Structure
Size Price Availability
5mg USD 60  USD60 Out of stock
10mg USD 90  USD90 Out of stock
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Quality Control & Documentation
Biological Activity

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Auristatin E is a highly potent antimitotic agent that inhibits tubulin polymerization. Auristatin E-antibody conjugates have proven to be successful anticancer agents.

Chemical Information
Molecular Weight 732.01
Formula C40H69N5O7
CAS Number 160800-57-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Dongwei Li, et al. Mol Cancer Ther. DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma

[2] Joseph A Francisco, et al. Blood. cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity

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Keywords: Auristatin E supplier, Microtubule, inhibitors, activators

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