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AR-13503

Cat. No. M40626

All AbMole products are for research use only, cannot be used for human consumption.

AR-13503 Structure

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Quality Control & Documentation
Biological Activity

AR-13503 is an active metabolite of Netarsudil and a PKC/ROCK inhibitor that inhibits angiogenesis and enhances retinal pigment epithelium (RPE) permeability. It can be used in studies related to diabetic macular edema and macular degeneration.

Chemical Information
Molecular Weight 321.37
Formula C19H19N3O2
CAS Number 1254032-16-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gary S L Peh et al. Cells. Effects of Rho-Associated Kinase (Rock) Inhibitors (Alternative to Y-27632) on Primary Human Corneal Endothelial Cells

[2] Brian Levy et al. Am J Ophthalmol. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers

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  Catalog
Abmole Inhibitor Catalog




Keywords: AR-13503 supplier, ROCK, inhibitors, activators

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