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Apcin-A 

Cat. No. M55917

All AbMole products are for research use only, cannot be used for human consumption.

Apcin-A  Structure

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Quality Control & Documentation
Biological Activity

Apcin-A, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor.

Chemical Information
Molecular Weight 342.61
Formula C10H14Cl3N5O2
CAS Number 1683617-62-0
Form Solid
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related APC Products
Apcin-A monohydrochloride 

Apcin-A monohydrochloride, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor.

TAME hydrochloride 

TAME hydrochloride is an inhibitor of anaphase-promoting complex/cyclosome (APC/C or APC), which binds to APC/C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest. TAME hydrochloride is not cell permeable.

proTAME 

proTAME, a cell-permeable proagent form of TAME, is an anaphase promoting complex/cyclosome (APC/C) inhibitor. proTAME causes cell cycle arrest in metaphase.

Apcin

Apcin, a ligand of Cdc20, is a potent and competitive anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity inhibitor. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. Apcin is a cdc20 inhibitor; inhibits Cdc20-substrate interaction.

  Catalog
Abmole Inhibitor Catalog




Keywords: Apcin-A  supplier, APC, inhibitors, activators

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