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Antimalarial agent 12 is a potent antimalarial agent. Antimalarial agent 12 shows growth inhibition on P. falciparum Dd2 Strain (EC50=155 nM), 3D7 strain (EC50=136 nM). Antimalarial agent 12 has CC50 values of 10,000 to 50,000 nM for HEK-293 and hPHep cell lines.
Molecular Weight | 505.79 |
Formula | C26H18BrClN2O2 |
CAS Number | 2715225-58-2 |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Anwei Hou et al. Chembiochem. Cladosporin, A Highly Potent Antimalaria Drug?
[5] Duong Nhu et al. Bioorg Med Chem Lett. Antimalarial 3-arylamino-6-benzylamino-1,2,4,5-tetrazines
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