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AN11251 

Cat. No. M29276

All AbMole products are for research use only, cannot be used for human consumption.

AN11251  Structure

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Quality Control & Documentation
Biological Activity

AN11251 is a potent and oral active anti-Wolbachia agent with potential for treatment of onchocerciasis and lymphatic filariasis, with EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines.

Chemical Information
Molecular Weight 528.42
Formula C29H38BFO7
CAS Number 2130750-59-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Ming-Jie Han, et al. Molecules. Assessing Boron-Pleuromutilin AN11251 for the Development of Antibacterial Agents

[2] Alexandra Ehrens, et al. PLoS Negl Trop Dis. In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis

[3] Robert T Jacobs, et al. J Med Chem. Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis

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  Catalog
Abmole Inhibitor Catalog




Keywords: AN11251  supplier, Parasite, inhibitors, activators

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