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Aminopurvalanol A

Cat. No. M11010

All AbMole products are for research use only, cannot be used for human consumption.

Aminopurvalanol A Structure
Synonym:

NG97

Size Price Availability Quantity
1mg USD 45  USD45 In stock
5mg USD 110  USD110 In stock
10mg USD 190  USD190 In stock
25mg USD 380  USD380 In stock
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Quality Control & Documentation
Biological Activity

Aminopurvalanol A is a selective, cell-permeable, reversible and ATP-competitive cyclin-dependent kinase (CDK) inhibitor, inhibiting cdk1/cyclin B, cdk2/cyclin A, cdk2/cyclin E, and cdk5/p35. Aminopurvalanol A causes the inhibition of sperm fertilizing ability via the inhibition of physiological capacitation-dependent actin polymerization.

Chemical Information
Molecular Weight 403.91
Formula C19H26ClN7O
CAS Number 220792-57-4
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nicola Bernabo, et al. Front Physiol . Aminopurvalanol A, a Potent, Selective, and Cell Permeable Inhibitor of Cyclins/Cdk Complexes, Causes the Reduction of in Vitro Fertilizing Ability of Boar Spermatozoa, by Negatively Affecting the Capacitation-Dependent Actin Polymerization

[2] G R Rosania, et al. Proc Natl Acad Sci U S A . A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts

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  Catalog
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Keywords: Aminopurvalanol A, NG97 supplier, CDK, inhibitors, activators

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