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α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy.
| Molecular Weight | 152.23 |
| Formula | C10H16O |
| CAS Number | 546-80-5 |
| Form | Liquid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Jens Bielenberg. Med Monatsschr Pharm. [Thujone]
[5] Dirk W Lachenmeier, et al. Forensic Sci Int. Thujone--cause of absinthism?
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