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Alizarin

Cat. No. M3332
Alizarin Structure
Synonym:

Anthraquinonic

Size Price Availability Quantity
50mg USD 40  USD40 In stock
100mg USD 50  USD50 In stock
1g USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Alizarin (Rubia, Rezza, alizarin crimson, crimson madder) is an organic compound and an important prominent dye. Alizarin is the main colorant found in the madder plant Rubia tinctorum. An orange-red crystalline compound used in making red pigments and in dyeing. Alizarin (Rubia, Rezza, alizarin crimson, crimson madder) is produced artificially from anthracene. Alizarin (Rubia, Rezza, alizarin crimson, crimson madder) produces the Turkish reds.

Chemical Information
Molecular Weight 240.21
Formula C14H8O4
CAS Number 72-48-0
Solubility (25°C) DMSO 38 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yaohong Ma, et al. Alizarin-graphene nanocomposite for calibration-free and online pH monitoring of microbial fuel cell

[2] Jian Zhang, et al. The mechanism of degradation of alizarin red by a white-rot fungus Trametes gibbosa

[3] Wen Wang, et al. Alizarin and Purpurin from Rubia tinctorum L. Suppress Insulin Fibrillation and Reduce the Amyloid-Induced Cytotoxicity

[4] Kıymet Berkil Akar. Evaluation of alizarin and purpurin dyes for their ability to visualize latent fingermark on porous surfaces

[5] Timothy J Mead. Alizarin Red and Alcian Blue Preparations to Visualize the Skeleton

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Keywords: Alizarin, Anthraquinonic supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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