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Afizagabar (S44819) is a first-in-class, competitive and selective α5-GABAAR antagonist with an IC50 value of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2.
| Molecular Weight | 365.38 |
| Formula | C19H12FN3O2S |
| CAS Number | 1398496-82-6 |
| Solubility (25°C) | DMSO : 6.25 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related GABA Receptor Products |
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| TPMPA
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| CI-966
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| NCS-382
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| CGS 8216
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