Free shipping on all orders over $ 500

Recently Added

Sign In
Sign Up
Contact Us

ACT-1004-1239

Cat. No. M21310

All AbMole products are for research use only, cannot be used for human consumption.

ACT-1004-1239 Structure

Size	Price	Availability	Quantity
5mg	USD 650 USD650	In stock
10mg	USD 1020 USD1020	In stock
25mg	USD 2100 USD2100	In stock

Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation

Purity: >99.0%
COA
MSDS

Product Information

Biological Activity

ACT-1004-1239 is a potent, selective, orally administered CXCR7 antagonist with an IC50 value of 3.2 nM.

Chemical Information

Molecular Weight	522.55
Formula	C27H28F2N6O3
CAS Number	2178049-58-4
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Christine Huynh, et al. Front Pharmacol. Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data

[2] Christine Huynh, et al. Biomed Pharmacother. Target engagement of the first-in-class CXCR7 antagonist ACT-1004-1239 following multiple-dose administration in mice and humans

[3] Laetitia Pouzol, et al. FASEB J. ACT-1004-1239, a first-in-class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseases

[4] Christine Huynh, et al. Clin Pharmacol Ther. A Multipurpose First-in-Human Study With the Novel CXCR7 Antagonist ACT-1004-1239 Using CXCL12 Plasma Concentrations as Target Engagement Biomarker

[5] Sylvia Richard-Bildstein, et al. J Med Chem. Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT-1004-1239

Related CXCR Products
Elubrixin Elubrixin (SB-656933) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
VUF 11222 VUF 11222 is a CXCR3 non-peptide-like agonist.
(±)-AMG 487 (±)-AMG 487 is a racemate of AMG 487.
Elubrixin tosylate Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
Elubrixin hydrochloride Elubrixin (SB-656933) hydrochloride is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.

Catalog

Abmole Inhibitor Catalog

Keywords: ACT-1004-1239 supplier, CXCR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.

Get to Know Us

Customer Support

Resources

Contact Us

Tel: +1-800-660-8580
Email: [email protected]

Tel: +32 (0)2 738 09 61
Email: [email protected]

Worldwide Distributors

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.