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ACBI2 is a potent, orally active VHL PROTAC SMARCA2 degrader (EC50: 7 nM) that degrades SMARCA2 (DC50: 1 nM in RKO cells).ACBI2 can be used in lung cancer research.
| Molecular Weight | 1064.16 |
| Formula | C56H68BrFN8O5S |
| CAS Number | 2913161-19-8 |
| Form | Solid |
| Solubility (25°C) | DMSO >100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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