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6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON) is an antibiotic isolated from Streptomyces, an antagonist of glutaminase with an IC50 value of about 1 mM for cKGA (renal glutamine). 6-Diazo-5-oxo-L-norleucine has analgesic, antibacterial, antiviral and anti-cancer properties.
| Molecular Weight | 171.15 |
| Formula | C6H9N3O3 |
| CAS Number | 157-03-9 |
| Form | Solid |
| Solubility (25°C) | Water ≥ 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Glutaminase Products |
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