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3-Methylxanthine

Cat. No. M20723

All AbMole products are for research use only, cannot be used for human consumption.

3-Methylxanthine Structure
Synonym:

3-MX

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Quality Control & Documentation
Biological Activity

3-Methylxanthine (3-MX), a 3-alkylxanthine, is an inhibitor of cyclic guanosine monophosphate (GMP) phosphodiesterase (PDE) with IC50 of 920 μM on guinea-pig isolated trachealis muscle.

Chemical Information
Molecular Weight 166.14
Formula C6H6N4O2
CAS Number 1076-22-8
Solubility (25°C) DMSO 8 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Binxing Zhou, et al. BMC Microbiol. 3-Methylxanthine production through biodegradation of theobromine by Aspergillus sydowii PT-2

[2] Khalid H R Algharrawi, et al. Microb Cell Fact. Direct conversion of theophylline to 3-methylxanthine by metabolically engineered E. coli

[3] Pedro M P Santos, et al. Redox Rep. Demethylation of theophylline (1,3-dimethylxanthine) to 1-methylxanthine: the first step of an antioxidising cascade

[4] T B Johnson, et al. Science. THE ATTEMPTED HYDROGENATION OF 3-METHYLXANTHINE

[5] R Sellman, et al. J Appl Toxicol. Kidney toxicity of 3-methylxanthine in the rat

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  Catalog
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Keywords: 3-Methylxanthine, 3-MX supplier, PDE, inhibitors, activators

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