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3-Bromopyruvate (3-Bromopyruvic acid)

Cat. No. M9680

All AbMole products are for research use only, cannot be used for human consumption.

3-Bromopyruvate (3-Bromopyruvic acid) Structure
Synonym:

Hexokinase II Inhibitor II; 3-BP

Size Price Availability Quantity
100mg USD 38  USD38 In stock
500mg USD 45  USD45 In stock
1g USD 55  USD55 In stock
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Quality Control & Documentation
Biological Activity

3-Bromopyruvate (3-Bromopyruvic acid) is a hexokinase II inhibitor, which is an effective antitumor agent on the hepatoma cells, with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is an inhibitor of tumour cell energy metabolism and chemopotentiator of platinum compounds.

Chemical Information
Molecular Weight 166.96
Formula C3H3BrO3
CAS Number 1113-59-3
Solubility (25°C) Water ≥ 30 mg/mL
Storage -20°C, dry, sealed, protect from light
References

[1] Izabela Sadowska-Bartosz, et al. Pharmacol Rep. Anticancer agent 3-bromopyruvic acid forms a conjugate with glutathione

[2] Lei Gong, et al. Anticancer Agents Med Chem. 3-Bromopyruvic acid, a hexokinase II inhibitor, is an effective antitumor agent on the hepatoma cells : in vitro and in vivo findings

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Keywords: 3-Bromopyruvate (3-Bromopyruvic acid), Hexokinase II Inhibitor II; 3-BP supplier, inhibitors, activators

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