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2-Hydroxycinnamaldehyde

Cat. No. M39854

All AbMole products are for research use only, cannot be used for human consumption.

2-Hydroxycinnamaldehyde Structure

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Quality Control & Documentation
Biological Activity

2-Hydroxycinnamaldehyde is a phenylpropanoid that can be isolated from the bark of Cinnamomum cassia. 2-Hydroxycinnamaldehyde inhibits Wnt/β-catenin, STAT3 signaling. 2-Hydroxycinnamaldehyde induces cell apoptosis 2-Hydroxycinnamaldehyde has antitumor and anti-inflammation activities.

Chemical Information
Molecular Weight 148.16
Formula C9H8O2
CAS Number 3541-42-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kyung-Sook Chung et al. Pharmaceutics. Regulation of ROS-Dependent JNK Pathway by 2'-Hydroxycinnamaldehyde Inducing Apoptosis in Human Promyelocytic HL-60 Leukemia Cells

[2] Lihua Hao et al. Exp Mol Med. 2'-Hydroxycinnamaldehyde ameliorates imiquimod-induced psoriasiform inflammation by targeting PKM2-STAT3 signaling in mice

[3] Yae Jin Yoon et al. Cancer Lett. 2'-hydroxycinnamaldehyde inhibits cancer cell proliferation and tumor growth by targeting the pyruvate kinase M2

[4] Hai-Anh Nguyen et al. Int J Oncol. 2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression

[5] Ismail Ahmed Ismail et al. Breast Cancer Res Treat. 2-Hydroxycinnamaldehyde inhibits the epithelial-mesenchymal transition in breast cancer cells

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Keywords: 2-Hydroxycinnamaldehyde supplier, Wnt/beta-catenin, inhibitors, activators

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