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1-EBIO

Cat. No. M6323

All AbMole products are for research use only, cannot be used for human consumption.

1-EBIO Structure
Size Price Availability Quantity
25mg USD 30  USD30 In stock
50mg USD 50  USD50 In stock
100mg USD 70  USD70 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

1-EBIO is a activator of epithelial KCa channels, stimulates a large and sustained trans-epithelial Cl- secretory response across T84 monolayers. Induces hyperpolarization to the same magnitude as ACh in aortic value endothelial cells. Promotes embryonic stem cell (ESC) differentiation into cardiomyocytes.

Chemical Information
Molecular Weight 162.19
Formula C9H10N2O
CAS Number 10045-45-1
Solubility (25°C) DMSO 16.22 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Giuseppe Manfroni, et al. New Insights on KCa3.1 Channel Modulation

[2] Corinna J Mohr, et al. Cancer-Associated Intermediate Conductance Ca 2+-Activated K⁺ Channel K Ca 3.1

[3] Eva K Roth, et al. The K+ channel opener 1-EBIO potentiates residual function of mutant CFTR in rectal biopsies from cystic fibrosis patients

[4] Julieta Garduo, et al. 1-Ethyl-2-benzimidazolinone (EBIO) suppresses epileptiform activity in in vitro hippocampus

[5] K L Hamilton, et al. 1-EBIO stimulates Cl- secretion by activating a basolateral K+ channel in the mouse jejunum

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Keywords: 1-EBIO supplier, Potassium Channel, inhibitors, activators

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