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1,4-Anthraquinone

Cat. No. M38916

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1,4-Anthraquinone Structure

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Biological Activity

1,4-Anthraquinone is a potent anticancer agent. 1,4-Anthraquinone blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of cancer cells. 1,4-Anthraquinone can be used to research anti-leukemia.

Chemical Information
Molecular Weight 208.21
Formula C14H8O2
CAS Number 635-12-1
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Vicky C Roa-Linares et al. Molecules. Anti-Herpetic, Anti-Dengue and Antineoplastic Activities of Simple and Heterocycle-Fused Derivatives of Terpenyl-1,4-Naphthoquinone and 1,4-Anthraquinone

[2] Rita Gatti et al. J Pharm Biomed Anal. 1,4-Anthraquinone: A new useful pre-column reagent for the determination of N-acetylcysteine and captopril in pharmaceuticals by high performance liquid chromatography

[3] Dan Du et al. Fitoterapia. 9,10-Dihydrophenanthrene derivatives and one 1,4-anthraquinone firstly isolated from Dioscorea zingiberensis C. H. Wright and their biological activities

[4] Chitoshi Kitamura et al. Acta Crystallogr Sect E Struct Rep Online. 6,7-Dimeth-oxy-1,4-anthraquinone

[5] E M Perchellet et al. Anticancer Drugs. 1,4-Anthraquinone: an anticancer drug that blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of L1210 leukemic cells in the same nanomolar range as daunorubicin in vitro

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Keywords: 1,4-Anthraquinone supplier, DNA/RNA Synthesis, inhibitors, activators

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