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VDAC Voltage-dependent anion channel

Cat.No.  Name Information
M45387 VBIT-4 VBIT-4 is a voltage-dependent anion channel (VDAC1) oligomer inhibitor with a Kd value of 17 μM.In addition, VBIT-4 is an inhibitor of apoptosis and can be used in studies related to neurodegenerative and cardiovascular diseases.
M11041 WEHI-9625 WEHI-9625 is a first-in-class tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX.
M9745 DIDS sodium salt DIDS sodium salt (MDL101114ZA) is a dual ABCA1 and VDAC1 inhibitor. DIDS sodium salt is also an anion transport inhibitor, which inhibits the ClC-Ka chloride channel and the bacterial ClC-ec1Cl-/H+ exchanger with IC50s of 100 μM and ~300 μM, respectively.
M9536 VBIT-12 VBIT-12 is a potent inhibitor of VDAC1, directly interacting with purified VDAC1 and reducing its channel conductance.
M31410 Tuvatexib Tuvatexib is a dual VDAC/HK2 small molecule modulator for studies related to squamous cell carcinoma.




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