Vasopressin Receptor Vasopressin Receptor

Cat.No.	Name	Information
M3480	Tolvaptan	Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation.
M11395	Lixivaptan	Lixivaptan (VPA-985, WAY-VPA 985) is an orally active, selective vasopressin receptor V2 antagonist with IC50 values of 1.2 nM in humans and 2.3 nM in rats.
M5166	Conivaptan hydrochloride	Conivaptan hydrochloride is a non-peptide vasopressin receptor antagonist, which can inhibit V1A receptor in rat liver and V2 receptor in kidney with Ki values of 0.48 and 3.04 nM, respectively.
M30218	SRX246	SRX246 is a potent, CNS-penetrant, highly selective, orally bioavailable vasopressin 1a (V1a) receptor antagonist (Ki=0.3 nM for human V1a). SRX246 has no interaction at V1b and V2 receptors. SRX246 also displays negligible binding at 64 others receptors classes, including 35 G-proteincoupled receptors. SRX246 can be used for treatment of stress-related disorders.
M25410	Nelivaptan	Nelivaptan (SSR-149415) is a vasopressin V1b receptor antagonist.
M25409	Satavaptan	Satavaptan (SR 121463) is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis.
M8178	SR 49059	SR 49059 is a potent and selective Arginine Vasopressin (AVP) V1a-receptor antagonist, with a Ki vaule of 1.4 nM.
M7356	TASP 0390325	TASP0390325 is a potent and orally active arginine vasopressin receptor 1B (V1B receptor) antagonist with antidepressant and anxiolytic activities in rodents.