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Conivaptan hydrochloride

Cat. No. M5166

All AbMole products are for research use only, cannot be used for human consumption.

Conivaptan hydrochloride Structure
Synonym:

Conivaptan HCl, Vaprisol, YM 087

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 70  USD70 In stock
5mg USD 40  USD40 In stock
10mg USD 65  USD65 In stock
50mg USD 250  USD250 In stock
100mg USD 440  USD440 In stock
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Quality Control & Documentation
Biological Activity

Conivaptan hydrochloride is a non-peptide vasopressin receptor antagonist, which can inhibit V1A receptor in rat liver and V2 receptor in kidney with Ki values of 0.48 and 3.04 nM, respectively.

Product Citations
Chemical Information
Molecular Weight 535.04
Formula C32H26N4O2.HCl
CAS Number 168626-94-6
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Wada K, et al. Eur J Pharmacol. Intravenous administration of conivaptan hydrochloride improves cardiac hemodynamics in rats with myocardial infarction-induced congestive heart failure.

[2] Fernandez-Varo G, et al. J Hepatol. Effect of the V1a/V2-AVP receptor antagonist, Conivaptan, on renal water metabolism and systemic hemodynamics in rats with cirrhosis and ascites.

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Keywords: Conivaptan hydrochloride, Conivaptan HCl, Vaprisol, YM 087 supplier, Vasopressin Receptor, inhibitors, activators

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