Trk Trk receptor

Cat.No.	Name	Information
M6151	Larotrectinib (LOXO-101)	Larotrectinib (LOXO-101) is a potent, ATP competitive TRK inhibitor with IC50s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100x selectivity over other kinases, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.
M28931	Anizatrectinib	Anizatrectinib (hTrkA-IN-1) is a potent and orally active inhibitor of TrkA kinase with an IC50 of 1.3 nM. Anizatrectinib can be used for the study of inflammatory disease, such as prostatitis, pelvic, et al.
M24972	Bedinvetmab	Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs.
M21319	CG428	CG428 is a TRK kinase fusion protein degrader.
M14581	Tavilermide	Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.
M8106	PF-06733804	PF-06733804 is pan tropomyosin-related kinase (Trk) inhibitor.
M8105	PF-06737007	PF-06737007 is pan tropomyosin-related kinase (Trk) inhibitor.
M8104	PF-06683324	PF-0668324 is pan tropomyosin-related kinase (Trk) inhibitor.