Inhibitor
| Cat.No. | Name | Information |
|---|---|---|
| M11403 | A939572 | A939572 is a potent, orally active stearyl CoA desaturase 1 SCD1 inhibitor that acts on mSCD1 and hSCD1 with IC50 <4 nM and 37 nM, respectively. |
| M10747 | GSK1940029 | GSK1940029 (SCD inhibitor 1) is a potent acyl-CoA desaturase (SCD) inhibitor. |
| M9502 | CVT-12012 | CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively. |
| M9212 | Aramchol | Aramchol is a novel fatty acid bile acid coupling agent with oral activity and an inhibitor of SCD1, which acts by inhibiting SCD1 expression in hepatocytes and hepatic astrocytes, and can be used in studies related to non-alcoholic steatohepatitis (NASH). |
| M42615 | SSI-4 | SSI-4 is an inhibitor of Stearoyl CoA desaturase 1 (SCD1) , which can be modified with 11C, used as a ligand to in vivo small animal PET/CT imaging of SCD1. |
| M29375 | YTX-465 | YTX-465 is a stearoyl-CoA desaturase (Ole1/SCD) inhibitor. YTX-465 inhibits Ole1 and SCD1 with IC50s of 0.039 μM and 30.4 μM, respectively. YTX-465 can be used in the research of Parkinson’s disease and other synucleinopathies. |
| M28127 | SCD1 inhibitor-4 | SCD1 inhibitor-4 is a potent, orally active stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes. |
| M28115 | SCD1 inhibitor-3 | SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II diabetes and dyslipidemia, as well as skin diseases, acne and cancer. |
| M27645 | CVT-11127 | CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer. |
| M19384 | Elemicin | Elemicin inhibits Stearoyl-CoA Desaturase 1 (SCD1) by metabolic activation. Elemicin has antimicrobial, antioxidant, and antiviral activities. Elemicin possesses genotoxicity and carcinogenicity. |
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