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CAY10566 is a potent and selective inhibitor of SCD1 (stearoyl-CoA desaturase1) that demonstrates IC50 values of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. CAY10566 treatment decreases Swiss 3T3 cell proliferation with concentration of 0.0001-10 μM. CAY10566 (2.5 mg/kg; orally twice daily) has great effect on mice with tumors.
| Molecular Weight | 389.81 |
| Formula | C18H17ClFN5O2 |
| CAS Number | 944808-88-2 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Stearoyl-CoA Desaturase Products |
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| T-3764518
T-3764518 is a novel and potent stearoyl coenzyme A desaturase (SCD) inhibitor with an IC50 of 4.7 nM. |
| Flurtamone
Flurtamone is a chiral herbicide with acute toxicity levels to Selenastrum capricornutum. |
| SSI-4
SSI-4 is an inhibitor of Stearoyl CoA desaturase 1 (SCD1) , which can be modified with 11C, used as a ligand to in vivo small animal PET/CT imaging of SCD1. |
| YTX-465
YTX-465 is a stearoyl-CoA desaturase (Ole1/SCD) inhibitor. YTX-465 inhibits Ole1 and SCD1 with IC50s of 0.039 μM and 30.4 μM, respectively. YTX-465 can be used in the research of Parkinson’s disease and other synucleinopathies. |
| SCD1 inhibitor-4
SCD1 inhibitor-4 is a potent, orally active stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes. |
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