| Cat.No. | Name | Information |
|---|---|---|
| M66392 | Recombinant Mouse Apolipoprotein H/APOH (HEK293, C-6His) | Apolipoprotein H/APOH proteins have multiple functions and can bind to negatively charged substances such as heparin and phospholipids. Its diverse interactions highlight the adaptability that is critical for preventing activation of the intrinsic coagulation cascade by binding to phospholipids on the surface of damaged cells. |
| M66340 | Recombinant Human BPIFB1 Protein (HEK293, C-His) | BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cells within the diseased epithelium, plays a role in the pathogenesis of the disease. BPIFB1 functions in the complex milieu that protects the mucosal surfaces in these locations. |
| M66319 | Recombinant Human TOMM20 Protein (E. coli, N-GST & C-His) | TOMM20, also known as Translocase of Outer Mitochondrial Membrane 20, is a crucial component of the translocase of the outer mitochondrial membrane (TOM) complex. It acts as a receptor on the outer mitochondrial membrane, recognizing and binding to mitochondrial pre - proteins, facilitating their import into the mitochondria. Dysfunction of TOMM20 has been linked to various mitochondrial - related diseases, such as neurodegenerative disorders. |
| M66311 | Recombinant Human TFAM Protein (E. coli, N-His) | TFAM regulates lymphangiogenesis, interacts with TEK/TIE2 and ITGA5, and binds to the mitochondrial light chain promoter. It is part of the mitochondrial transcription initiation complex formed with TFB2M and POLRMT and is critical for accurate promoter recognition and transcription initiation. |
| M66298 | Recombinant Human Intelectin-1/ITLN1 Protein (E. coli, N-His) | Intelectin-1/ITLN1 is a lectin with specific affinity for microbial carbohydrate chains and recognizes β-linked D-galactofuranosose, D-glycerolphosphate modified glycans, D-glycerol-D-talo-oct- 2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-keto acid (KDO). It binds to bacterial glycans and helps defend against microorganisms. |
| M66256 | Recombinant Listeria monocytogenes flagellin Protein (E. coli, N-His) | Flagellin is a subunit protein of bacterial flagellum. |
| M66231 | Recombinant Human UCP2 Protein (E. coli, N-His) | UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. |
| M66186 | Recombinant Human S100A8 & S100A9 Protein (Baculovirus-Insect, C-His & C-Flag) | Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. It contributes to leukocyte function, regulates the cytoskeleton, and activates intracellular NADPH oxidase. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. |
| M59321 | Recombinant Human COL6A3 Protein (HEK293) | COL6A3 protein is an important component of type VI collagen and has the function of a cell-binding protein. |
| M59315 | Recombinant Human SAA2 Protein (E. coli, N-6His) | Serum amyloid A-2 protein (SAA2) belongs to the SAA family. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. |
| M59111 | Recombinant Human S100P (E. coli, N-6His) | Protein S100-P (S100P) belongs to the S100 family of Calcium-Binding Proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and it is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. In addition to binding Ca, S100P also binds Zn and Mg, and may play a role in the etiology of prostate cancer. |
| M59083 | Recombinant Human GSDMD Protein (E. coli, N-His) | GSDMD (Gasdermin D) is a protein that plays a crucial role in pyroptosis, a highly inflammatory form of cell death. It acts as a pore-forming protein, creating openings in the cell membrane and triggering the release of inflammatory molecules like interleukin-1β. |
| M59064 | Recombinant Human TSPAN13 Protein (E. coli, C-His) | Recombinant Human TSPAN13 Protein expressed the target gene encoding Cys94-Glu164 with a polyhistidine tag at the C-terminus. |
| M59059 | Recombinant Human SAA1 Protein (E. coli, N-6His) | Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. |
| M59008 | Recombinant Human IMPDH2 Protein (E. coli, N-His) | Recombinant Human IMPDH2 Protein (E. coli, N-His) expressed the target gene encoding Asp226-Phe514 with a His tag at the N-terminus. |
| M58950 | Recombinant Human Semaphorin 5A (HEK293, C-6His) | Semaphorin-5A (SEMA5A) is a member of the Semaphorin family of axon guidance molecules. SEMA5A mutations have been implicated in the genetic syndrome,cri-du-chat,while some polymorphisms may increase risk for neurodegenerative diseases such as Parkinson. The expression of SEMA5A may be upregulated in metastatic cancer cells and downregulated in autism. |
| M58942 | Recombinant Human TRIM21 Protein (E. coli, N-His) | TRIM21 Protein, an E3 ubiquitin ligase, plays a vital role in the immune response by targeting intracellular pathogens for degradation. It is involved in the recognition and clearance of viral particles. E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. |
| M58628 | Recombinant Mouse Progranulin Protein (HEK293, C-His) | Progranulin (PGRN) proteins regulate lysosomal function, affecting protein transport, enzymatic activity, and acidification. It degrades mature cathepsin D via cathepsin B. The precursor protein, progranulin, is also called Proepithelin and PC cell-derived growth factor. Granulin family members are important in normal development, wound healing, and tumorigenesis. Granulins have possible cytokine-like activity. |
| M55397 | Recombinant Human HMGB1 Protein (E. coli) | High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses. |
| M55380 | Recombinant Human SEMA3A (HEK293, N-6His-Flag) | Semaphorin 3A (SEMA3A) is a secreted protein which belongs to the semaphorin family. Semaphorin 3A can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. |
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