Inhibitor
| Cat.No. | Name | Information |
|---|---|---|
| M41550 | N4-Methylcytidine | N4-Methylcytidine (Nsc518744) is a cytidine nucleoside analog. |
| M41549 | N-6-Methyl-2-deoxyadenosine | N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. |
| M41548 | N6-Benzoyl-9-β-D-arabinofuranosyladenine | N6-Benzoyl-9-β-D-arabinofuranosyladenine is an adenosine analog. |
| M41547 | S-Gem | S-Gem is a TrxR-dependent precursor of Gemcitabine and selectively activated by TrxR. |
| M41546 | Dihydro-5-azacytidine acetate | Dihydro-5-azacytidine acetate (DHAC), the nucleoside analog, is incorporated into DNA and inhibits DNA methylation. |
| M38941 | Isoguanine | Isoguanine is a purine base that is an isomer of Guanine. A building block in organic synthesis. |
| M38940 | 3'-Deoxycytidine | 4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (3'-Deoxycytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. |
| M38939 | 6-Chloroguanineriboside | 6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
| M38938 | 5-Fluoro-5'-deoxycytidine | 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine), and have potential anti-metabolic and anti-tumor activities. |
| M38936 | N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine | N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) is an useful tool for probing enzyme-catalyzed cleavage processes in DNA. |
| M30297 | Enocitabine | Enocitabine is a nucleoside analog, and is a potent DNA replication inhibitor, and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus. Enocitabine has antileukemic and antiviral activities. |
| M30016 | CCPA | CCPA (2-Chloro-N6-cyclopentyladenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
| M29670 | Spongosine | Spongosine (2-Methoxyadenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
| M29183 | 2-Methylthio isopentenyladenosine | 2-Methylthio isopentenyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
| M29150 | 2'-O,4'-C-Methyleneadenosine | 2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog. |
| M28944 | FF-10502 | FF-10502, a structural analog of Gemcitabine, is a pyrimidine nucleoside antimetabolite. FF-10502 inhibits DNA polymerase α and β. FF-10502 shows beneficial anticancer activity via a mechanism of action on dormant cells. |
| M28560 | Sapacitabine | Sapacitabine is an orally available nucleoside analog proagent that is structurally related to cytarabine. |
| M28434 | 5'-Amino-5'-deoxyadenosine | 5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
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