NEDD8-activating Enzyme NEDD8-activating Enzyme

Cat.No.	Name	Information
M2189	Pevonedistat	Pevonedistat (MLN4924) is a first-of-its-kind (first-in-class) small molecule inhibitor of Nedd8 activating enzyme (NAE) with an IC50 of 4.7 nM.
M45362	NAE-IN-M22	NAE-IN-M22 is a potent, selective, and reversible inhibitor of NEDD8-activating enzyme (NAE) in the micromolar range. In addition, NAE-IN-M22 inhibits the growth of various cancer cells and induces apoptosis in A549 cells.
M10755	TAS4464	TAS4464 is a highly selective inhibitor of NEDD8 activated enzyme (NAE),IC50 The value is 0.955 nM.
M56727	ZM223	ZM223 is a potent non-covalent NEDD8 activating enzyme (NAE) inhibitor, orally active.
M45363	ZM223 hydrochloride	ZM223 hydrochloride is a potent, orally active, non-covalent NEDD8 activating enzyme (NAE) inhibitor.
M14478	TAS4464 hydrochloride	TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.
M14477	Pevonedistat hydrochloride	Pevonedistat hydrochloride (MLN4924 hydrochloride) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC50 of 4.7 nM.