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Pevonedistat hydrochloride

Cat. No. M14477

All AbMole products are for research use only, cannot be used for human consumption.

Pevonedistat hydrochloride Structure
Synonym:

MLN4924 hydrochloride

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Quality Control & Documentation
Biological Activity

Pevonedistat hydrochloride (MLN4924 hydrochloride) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC50 of 4.7 nM.

Chemical Information
Molecular Weight 479.98
CAS Number 1160295-21-5
Solubility (25°C) DMSO 90 mg/mL
Water 10 mg/mL
Storage 2-8°C, dry, sealed
References

[1] C Paiva, et al. Cell Death Dis. Targeting neddylation induces DNA damage and checkpoint activation and sensitizes chronic lymphocytic leukemia B cells to alkylating agents

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  Catalog
Abmole Inhibitor Catalog




Keywords: Pevonedistat hydrochloride, MLN4924 hydrochloride supplier, NEDD8-activating Enzyme, inhibitors, activators

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