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ZM223 hydrochloride is a potent, orally active, non-covalent NEDD8 activating enzyme (NAE) inhibitor.
| Molecular Weight | 538.99 |
| Formula | C23H18ClF3N4O2S2 |
| CAS Number | 2438679-27-5 |
| Form | Solid |
| Solubility (25°C) | DMSO >100 mg/mL |
| Storage | 4°C, dry, sealed |
| Related NEDD8-activating Enzyme Products |
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| ZM223
ZM223 is a potent non-covalent NEDD8 activating enzyme (NAE) inhibitor, orally active. |
| NAE-IN-M22
NAE-IN-M22 is a potent, selective, and reversible inhibitor of NEDD8-activating enzyme (NAE) in the micromolar range. In addition, NAE-IN-M22 inhibits the growth of various cancer cells and induces apoptosis in A549 cells. |
| TAS4464 hydrochloride
TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM. |
| Pevonedistat hydrochloride
Pevonedistat hydrochloride (MLN4924 hydrochloride) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC50 of 4.7 nM. |
| TAS4464
TAS4464 is a highly selective inhibitor of NEDD8 activated enzyme (NAE),IC50 The value is 0.955 nM. |
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