| Cat.No. | Name | Information |
|---|---|---|
| M50191 | MRGPRX1 agonist 1 | MRGPRX1 agonist 1 is a potent Mas-related G protein-coupled receptor X1 (MRGPRX1) agonist with an EC50 value of 50 nM and is inactive against MRGPRC11. |
| M50190 | MrgprX2 antagonist-8 | MrgprX2 antagonist-8 is a MrgprX2 antagonist for studies related to inflammatory diseases. |
| M53100 | Neuropeptide AF (cattle) | Neuropeptide AF (cattle), an amidated octadecapeptide, is RFamide neuropeptide. |
| M50195 | (S)-ZINC-3573 | (S)-ZINC-3573 is an inactive enantiomer of ZINC-3573 and a selective MRGPRX2 agonist. In addition, (S)-ZINC-3573 and (R)-ZINC-3573 are potent internal control probes that can be used to study the biology of unique receptors in primates. |
| M50194 | MRGPRX4 modulator-2 | MRGPRX4 modulator-2 is a potent MRGPR X4 modulator with antagonistic activity against MRGPRX4 and an IC50 < 100 nM.MRGPRX4 modulator-2 can be used in studies related to autoimmune diseases. |
| M50193 | MRGPRX4 modulator-1 | MRGPRX4 modulator-1 is a potent MAS-associated G-protein receptor X4 (MRGPRX4) modulator with antagonistic activity against MRGPR4 and an IC50 < 100 nM.MRGPRX4 modulator-1 can be used in studies related to MRGPRX4-dependent disorders, such as itch, pain, and autoimmune diseases. |
| M50192 | PAMP-12 | PAMP-12 is an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM) that induces hypotension by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells. |
| M50189 | MS47134 | MS47134 is a potent and selective MRGPRX4 agonist with an EC50 of 149 nM.MS47134 can be used in studies related to pain, pruritus, and mast cell-mediated hypersensitivity. |
| M50188 | MrgprX2 antagonist-1 | MrgprX2 antagonist-1 is an antagonist of MrgprX2 that can be used in studies related to inflammatory skin diseases. |
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