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Methionine Adenosyltransferase Methionine adenosyltransferases (MATs)

Inhibitor

Cat.No.  Name Information
M55363 IDE397 IDE397 (GSK-4362676) is a potent, potential "first-in-class" inhibitor of methionine adenosyltransferase 2A (MAT2A). IDE397 (GSK-4362676) exhibits anti-tumor activity in MTAP-deleted PDX models.
M10762 AG-270 AG-270 is a non-competitive, first-of-its-kind, reversible, orally active MAT2A allogeneic inhibitor IC50 The value is 14 nM.
M10056 FIDAS-5 FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM.
M9788 PF-9366 PF-9366 is a novel inhibitor of human methionine adenosyltransferase 2A (Mat2A), with IC50 of 420 nM and Kd of 170 nM.
M41721 MAT2A-IN-10 MAT2A-IN-10 is an orally active MAT2A inhibitor with an IC50 of 26 nM.
M41720 MAT2A-IN-12 MAT2A Allosteric inhibitor 2 is a potent and selective MAT2A allosteric inhibitor with an IC50 of 5 nM.
M29642 MAT2A inhibitor 3  MAT2A inhibitor 3 is a methionine adenosyltransferase 2A (MAT2A) inhibitor, with an IC50 of <200 nM. MAT2A inhibitor 3 can be used for the research of cancers.
M28179 MAT2A inhibitor 2  MAT2A inhibitor 2 is a methionine adenosyltransferase 2A (MAT2A) inhibitor.




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