Cat.No. | Name | Information |
---|---|---|
M2225 | Thalidomide | Thalidomide is a sedative and immunomodulator used to study the symptoms of many cancers, it has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM. |
M57119 | (S,R,S)-AHPC-Boc | (S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. |
M57118 | Lenalidomide-Br | Lenalidomide-Br is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. |
M57117 | CRBN modulator-1 | CRBN modulator-1, a Thalidomide analog and a CRBN modulator, has an IC50 of 3.5 μM and a Ki of 0.98 μM. |
M57116 | Lenalidomide-4-OH | Lenalidomide-4-OH is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. |
M57115 | (S,R,S)-AHPC TFA | (S,R,S)-AHPC (VH032-NH2) TFA is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. |
M57114 | Nutlin carboxylic acid | Nutlin carboxylic acid (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand. |
M57113 | cIAP1 ligand 1 | cIAP1 ligand 1 is the LCL161 derivative based IAP ligand. |
M57112 | Pomalidomide-piperazine | Pomalidomide-piperazine is an active compound that can be used to synthesis the E3 ligand for PROTAC. |
M57111 | (S,R,S)-AHPC dihydrochloride | (S,R,S)-AHPC (VH032-NH2) dihydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. |
M43915 | 2,6-bis(benzyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | 2,6-bis(benzyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine |
M43914 | 2,6-Bis(benzyloxy)pyridine-3-boronic acid | 2,6-Bis(benzyloxy)pyridine-3-boronic acid |
M43912 | 2,6-bis(benzyloxy)pyridin-3-amine | 2,6-bis(benzyloxy)pyridin-3-amine |
M43910 | 3-[2,5-Difluoro-4-(4-piperidinyl)phenyl]-2,6-piperidinedione | 3-[2,5-Difluoro-4-(4-piperidinyl)phenyl]-2,6-piperidinedione |
M43905 | 2,6-Piperidinedione, 3-[4-(4-piperidinyl)phenoxy]- | 2,6-Piperidinedione, 3-[4-(4-piperidinyl)phenoxy]- |
M43904 | 2-Pyridinecarboxamide, N-(2,6-dioxo-3-piperidinyl)-5-(1-piperazinyl)- | 2-Pyridinecarboxamide, N-(2,6-dioxo-3-piperidinyl)-5-(1-piperazinyl)- |
M43903 | 2,6-Piperidinedione, 3-[[6-(1-piperazinyl)-3-pyridinyl]amino]- | 2,6-Piperidinedione, 3-[[6-(1-piperazinyl)-3-pyridinyl]amino]- |
M43902 | 2,6-Piperidinedione, 3-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]- | 2,6-Piperidinedione, 3-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]- |
M43899 | 2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]- | 2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]- |
M43898 | 3-((4-(piperidin-4-yl)phenyl)amino)piperidine-2,6-dione | 3-((4-(piperidin-4-yl)phenyl)amino)piperidine-2,6-dione |
M43895 | tert-butyl 4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidine-1-carboxylate | tert-butyl 4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidine-1-carboxylate |
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