| Cat.No. | Name | Information |
|---|---|---|
| M2225 | Thalidomide | Thalidomide is a sedative and immunomodulator used to study the symptoms of many cancers, it has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM. |
| M43862 | 4-Piperidinecarboxaldehyde, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]- | 4-Piperidinecarboxaldehyde, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]- |
| M43861 | 4-Piperidinecarboxylic acid, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]-, 1,1-dimethylethyl ester | 4-Piperidinecarboxylic acid, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]-, 1,1-dimethylethyl ester |
| M43860 | 1-[5-(2,6-Dioxo-3-piperidinyl)-3-fluoro-2-pyridinyl]-4-piperidineacetic acid | 1-[5-(2,6-Dioxo-3-piperidinyl)-3-fluoro-2-pyridinyl]-4-piperidineacetic acid |
| M43859 | 3-[6-[4-(Hydroxymethyl)-1-piperidinyl]-3-pyridinyl]-2,6-piperidinedione | 3-[6-[4-(Hydroxymethyl)-1-piperidinyl]-3-pyridinyl]-2,6-piperidinedione |
| M43858 | 3-[6-[4-(Methylamino)-1-piperidinyl]-3-pyridinyl]-2,6-piperidinedione | 3-[6-[4-(Methylamino)-1-piperidinyl]-3-pyridinyl]-2,6-piperidinedione |
| M43857 | 3-[6-(4-Amino-1-piperidinyl)-3-pyridinyl]-2,6-piperidinedione | 3-[6-(4-Amino-1-piperidinyl)-3-pyridinyl]-2,6-piperidinedione |
| M43856 | 3-[6-(1-Piperazinyl)-3-pyridinyl]-2,6-piperidinedione | 3-[6-(1-Piperazinyl)-3-pyridinyl]-2,6-piperidinedione |
| M43855 | 4-Piperidinecarboxaldehyde, 1-[6-(2,6-dioxo-3-piperidinyl)-3-pyridinyl]- | 4-Piperidinecarboxaldehyde, 1-[6-(2,6-dioxo-3-piperidinyl)-3-pyridinyl]- |
| M43854 | 3-(3-fluoro-4-(piperidin-4-yl)phenyl)piperidine-2,6-dione | 3-(3-fluoro-4-(piperidin-4-yl)phenyl)piperidine-2,6-dione |
| M43853 | 1-(4-(piperidin-4-yl)phenyl)dihydropyrimidine-2,4(1H,3H)-dione | 1-(4-(piperidin-4-yl)phenyl)dihydropyrimidine-2,4(1H,3H)-dione |
| M43852 | 3-(4-(piperidin-4-yl)phenyl)piperidine-2,6-dione | 3-(4-(piperidin-4-yl)phenyl)piperidine-2,6-dione |
| M43851 | 1-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-4-piperidineacetic acid | 1-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-4-piperidineacetic acid |
| M43850 | 2-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-2-azaspiro[3.3]heptane-6-acetic acid | 2-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-2-azaspiro[3.3]heptane-6-acetic acid |
| M43848 | 2,6-Piperidinedione, 3-[6-(4-piperidinyl)-3-pyridinyl]- | 2,6-Piperidinedione, 3-[6-(4-piperidinyl)-3-pyridinyl]- |
| M43847 | 1-(4-(2,6-dioxopiperidin-3-yl)phenyl)piperidine-4-carbaldehyde | 1-(4-(2,6-dioxopiperidin-3-yl)phenyl)piperidine-4-carbaldehyde |
| M43846 | 3-(4-(4-(hydroxymethyl)piperidin-1-yl)phenyl)piperidine-2,6-dione | 3-(4-(4-(hydroxymethyl)piperidin-1-yl)phenyl)piperidine-2,6-dione |
| M43845 | 3-[4-[3,3-Difluoro-4-(methylamino)-1-piperidinyl]phenyl]-2,6-piperidinedione | 3-[4-[3,3-Difluoro-4-(methylamino)-1-piperidinyl]phenyl]-2,6-piperidinedione |
| M43424 | CRBN ligand-9 | CRBN ligand-9 is a CRBN ligand (Ki: 8.9 μM). |
| M43423 | CC-3060 | CC-3060 is a Cereblon modulator that promotes ZBTB16 degradation. |
| M43422 | DCAF1 binder 1 | DCAF1 binder 1 is a selective for the CRL4 DCAF1 E3 ligase complex. |
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