Ketohexokinase Ketohexokinase

Cat.No.	Name	Information
M43110	KHK-IN-3	KHK-IN-3 is a ketohexokinase (KHK) inhibitor.
M29288	KHK-IN-2	KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with an IC50 of 0.45 μM.
M28139	KHK-IN-1 hydrochloride	KHK-IN-1 hydrochloride (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 hydrochloride inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 hydrochloride has potential for the study of diabetes and obesity.
M28138	KHK-IN-1	KHK-IN-1 (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 has potential for the study of diabetes and obesity.
M21287	PF-06835919	PF-06835919 is an oral Class I clinical candidate for NAFLD/NASH, targeting ketohexokinase (KHK), an enzyme that initiates fructose metabolism.