| Cat.No. | Name | Information |
|---|---|---|
| M2568 | IDO-IN-2 (NLG-919 Analogue) | NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM. |
| M11556 | NLG-919 (Navoximod) | Navoximod (GDC-0919; Nlg-919) is an effective IDO (indoleamine-(2,3)-dioxygenase) inhibitor with Ki/EC50 of 7 nM/75 nM respectively. |
| M10116 | LM10 | LM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). |
| M58372 | (S)-LY-3381916 | (S)-LY-3381916 is an active S-isomer of LY-3381916. (S)-LY-3381916 binds to IDOL with an IC50 value less than 1.5 µΜ. LY-3381916 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. |
| M58329 | IDO2-IN-1 | IDO2-IN-1 is an orally active and potent Indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with an IC50 value of 112 nM. IDO2-IN-1 can be used for the research of inflammatory autoimmunity. |
| M56704 | IDO1/2-IN-1 | IDO1/2-IN-1 is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. |
| M56703 | IDO1/2-IN-1 hydrochloride | IDO1/2-IN-1 hydrochloride is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. |
| M42451 | IDO-IN-18 | IDO-IN-18 is an IDO inhibitor. |
| M42450 | IDO1-IN-21 | IDO1-IN-21 is an IDO1 inhibitor (IC50 = 0.64 μM). |
| M42449 | IDO1-IN-22 | IDO1-IN-22 is a IDO1 inhibitor (biochemical hIDO1 IC50: 67.4 nM, HeLa hIDO1 IC50: 17.6 nM). |
| M42448 | IDO1/TDO-IN-6 | IDO1/TDO-IN-6 is a dual inhibitor of IDO1/TDO with IC50s of 2.25 and 2.89 μM, respectively. |
| M29484 | IDO-IN-13 | IDO-IN-13 is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an EC50 of 17 nM, extracted from patent WO2019040102A1, example 43. |
| M29277 | Imsamotide | Imsamotide (IDO194-214) is a Indoleamine 2,3-Dioxygenase (IDO) peptide with sequences of DTLLKALLEIASCLEKALQVF, the IDO194-214. Imsamotide is also an immunological agent for active immunization, as well as an antineoplastic agent. |
| M21276 | NLG802 | NLG802 is a prodrug of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor. |
| M21233 | IDO1/TDO-IN-4 | IDO1/TDO-IN-4 is a potent dual IDO1/TDO inhibitor with IC50 values of 3.53 μM (IDO1) and 1.15 μM (TDO). IDO1/TDO-IN-4 forms hydrogen bonds with IDO1 and interacts with TDO in π-π stacking. IDO1/TDO-IN-4 can be used in the study of depression, as well as depression-induced infectious, metabolic and autoimmune diseases. |
| M10799 | BMS-986242 | BMS-986242 is an orally active, potent and selective indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor. BMS-986242 can be used in cancer research. |
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