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DGAT Diacylglycerol O-acyltransferase

Cat.No.  Name Information
M21575 Ervogastat Ervogastat is a DGAT2 inhibitor that can be used in studies related to non-alcoholic steatohepatitis (NASH).
M8388 T863 T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells.
M8069 PF-06424439 methanesulfonate PF-06424439 methanesulfonate is a potent and selective inhibitor of diacylglycerol acyltransferase 2 (DGAT2) with an IC50 of 14 nM.
M2926 PF-04620110 PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
M2722 AZD7687 AZD7687 is a reversible and selective DGAT1 inhibitor with IC50 value of 80 nM.
M2059 A-922500 A-922500 (DGAT-1 Inhibitor 4a) is a potent and selective DGAT-1 inhibitor with IC50 values of 9 and 22 nM at human and mouse DGAT-1 respectively.
M45062 PF-07202954 PF-07202954 is an orally active, weakly basic DGAT2 inhibitor with an IC50 of 10 nM for human DGAT2.PF-07202954 reduces hepatic triglycerides in an obese rat model.
M40987 ION224 ION224 is an antisense compound that targets DGAT-2 for studies related to non-alcoholic steatohepatitis (NASH).
M40981 PF-07055341 PF-07055341 is a DGAT1/2 inhibitor that can be used in studies related to non-alcoholic steatohepatitis (NASH).
M14292 Pradigastat Pradigastat (LCQ-908) is a potent, selective and orally active diacylglycerol acyltransferase 1 (DGAT1) inhibitor. Pradigastat has anti-obesity and anti-diabetic effects.
M14291 DGAT-1 inhibitor 2 DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1;antiobesity agents.
M6850 JNJ DGAT2-A JNJ DGAT2-A is a dGAT2 inhibitor.
M6482 AZD 3988 AZD 3988 is a potent and selective DGAT-1 inhibitor.




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