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PF-07202954

Cat. No. M45062

All AbMole products are for research use only, cannot be used for human consumption.

PF-07202954 Structure

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Quality Control & Documentation
Biological Activity

PF-07202954 is an orally active, weakly basic DGAT2 inhibitor with an IC50 of 10 nM for human DGAT2.PF-07202954 reduces hepatic triglycerides in an obese rat model.

Chemical Information
Molecular Weight 438.45
Formula C22H23FN6O3
CAS Number 2639372-47-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kevin J Filipski, et al. ACS Med Chem Lett. Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life

[2] Wujun Chen, et al. Cardiovasc Diabetol. The translational potential of miR-26 in atherosclerosis and development of agents for its target genes ACC1/2, COL1A1, CPT1A, FBP1, DGAT2, and SMAD7

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  Catalog
Abmole Inhibitor Catalog




Keywords: PF-07202954 supplier, DGAT, inhibitors, activators

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