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Bcl-2 B-cell lymphoma 2

Cat.No.  Name Information
M1637 ABT-263 ABT-263 (Navitoclax) is a potent, orally bioavailable inhibitor of the antiapoptotic Bcl-2 family members Bcl-2, Bcl-x (L), and Bcl-w.
M2017 ABT-199 (Venetoclax) ABT-199 is a highly potent, orally bioavailable and BCL-2 inhibitor. ABT-199 is the first inhibitor targeting Bcl-2 and PPI.
M5273 S63845 S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor; binds human MCL1 with a Kd of 0.19 nM.
M13528 AZD-5991 AZD-5991 is a potent and selective Mcl-1 inhibitor with an IC50 of 0.7 nM in FRET assay and a Kd of 0.17 nM in surface plasmon resonance (SPR) assay.
M13526 A-1155463 A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell.
M54126 Bim BH3, Peptide IV Bim BH3, Peptide IV is a 26-residue peptide from BH3-only protein Bim, which belongs to the pro-apoptotic group of the Bcl-2 family of proteins.
M53413 Bax inhibitor peptide, negative control Bax inhibitor peptide, negative control is a inhibitor of Bax.
M53412 Bad BH3 (mouse) Bad BH3 (mouse) is a biological active peptide.
M53411 Bid BH3 (80-99) Bid BH3 (80-99) is a biological active peptide.
M53410 Bak BH3 Bak BH3 is derived from the BH3 domain of Bak, can antagonize the function of Bcl-xL in cells.
M53409 F1324 F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM.
M45260 Pelcitoclax Pelcitoclax is a potent Bcl-2/Bcl-xl inhibitor with anti-tumor and pro-apoptotic activities.
M45060 ABBV-467 ABBV-467 is a type IV selective MCL-1 inhibitor for studies related to multiple myeloma.
M45050 Sonrotoclax Sonrotoclax is an orally active, potent Bcl2 inhibitor.Sonrotoclax exhibits potent cell killing effects on a variety of lymphoma and leukemia cell lines. Sonrotoclax is effective in killing a variety of lymphoma and leukemia cell lines and may be used in studies related to hematologic tumors.
M41328 WK499 BCL6-IN-10 is a BCL6 inhibitor.
M41327 Hrk BH3 Hrk BH3 is a biological active peptide.
M41326 Bik BH3 Bik BH3 is a biological active peptide.
M41325 Bim BH3 Bim BH3 is a biological active peptide.
M41324 Bcl-B inhibitor 1 Bcl-B inhibitor 1 is a Bcl-B inhibitor.
M41323 r8 Bid BH3 r8 Bid BH3 is a biological active peptide.
M41322 Mcl-1 inhibitor 15 Mcl-1 inhibitor 15 is a Mcl-1 inhibitor (Ki: 0.02 nM).
M41321 Lacutoclax Lacutoclax is a Bcl-2 inhibitor with antineoplastic activity.
M41320 Mcl-1 inhibitor 13 Mcl-1 inhibitor 13 is a MCL-1 inhibitor (Ki: 8.2 nM).
M41319 Mcl-1 inhibitor 12 Mcl-1 inhibitor 12 is a MCL-1 inhibitor (Ki: 0.22 nM).
M41318 Mcl-1 inhibitor 16 Mcl-1 inhibitor 16 is a mitochondrial targeting Platinum-based inhibitor of Mcl-1.




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