| Cat.No. | Name | Information |
|---|---|---|
| M1637 | ABT-263 | ABT-263 (Navitoclax) is a potent, orally bioavailable inhibitor of the antiapoptotic Bcl-2 family members Bcl-2, Bcl-x (L), and Bcl-w. |
| M2017 | ABT-199 (Venetoclax) | ABT-199 is a highly potent, orally bioavailable and BCL-2 inhibitor. ABT-199 is the first inhibitor targeting Bcl-2 and PPI. |
| M5273 | S63845 | S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor; binds human MCL1 with a Kd of 0.19 nM. |
| M13528 | AZD-5991 | AZD-5991 is a potent and selective Mcl-1 inhibitor with an IC50 of 0.7 nM in FRET assay and a Kd of 0.17 nM in surface plasmon resonance (SPR) assay. |
| M13526 | A-1155463 | A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell. |
| M1638 | ABT-737 | ABT-737 is a potent and selective inhibitor of B-cell lymphoma-2 (BCL-2) family proteins, in small cell lung cancer. |
| M55882 | ABBV-467 | ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). |
| M55881 | WEHI-539 | WEHI-539 is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM. |
| M55880 | (Rac)-Lisaftoclax | (Rac)-Lisaftoclax ((Rac)-APG-2575) is a Bcl-2 inhibitor that can be uesd for hematologic malignancy research. |
| M55879 | BcI-2/BcI-xI ligand 1 | BcI-2/BcI-xI ligand 1 is a BcI-2/BcI-xI ligand, and can be used for synthesis of PROTAC BcI-2/BcI-xI Degrader-1. |
| M55878 | AZD-5991 (S-enantiomer) | AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. |
| M54332 | BAD (103-127) (human) | BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD, can antagonize the function of Bcl-xL. |
| M54126 | Bim BH3, Peptide IV | Bim BH3, Peptide IV is a 26-residue peptide from BH3-only protein Bim, which belongs to the pro-apoptotic group of the Bcl-2 family of proteins. |
| M53413 | Bax inhibitor peptide, negative control | Bax inhibitor peptide, negative control is a inhibitor of Bax. |
| M53412 | Bad BH3 (mouse) | Bad BH3 (mouse) is a biological active peptide. |
| M53411 | Bid BH3 (80-99) | Bid BH3 (80-99) is a biological active peptide. |
| M53410 | Bak BH3 | Bak BH3 is derived from the BH3 domain of Bak, can antagonize the function of Bcl-xL in cells. |
| M53409 | F1324 | F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. |
| M45260 | Pelcitoclax | Pelcitoclax is a potent Bcl-2/Bcl-xl inhibitor with anti-tumor and pro-apoptotic activities. |
| M45060 | ABBV-467 | ABBV-467 is a type IV selective MCL-1 inhibitor for studies related to multiple myeloma. |
| M45050 | Sonrotoclax | Sonrotoclax is an orally active, potent Bcl2 inhibitor.Sonrotoclax exhibits potent cell killing effects on a variety of lymphoma and leukemia cell lines. Sonrotoclax is effective in killing a variety of lymphoma and leukemia cell lines and may be used in studies related to hematologic tumors. |
| M41328 | WK499 | BCL6-IN-10 is a BCL6 inhibitor. |
| M41327 | Hrk BH3 | Hrk BH3 is a biological active peptide. |
| M41326 | Bik BH3 | Bik BH3 is a biological active peptide. |
| M41325 | Bim BH3 | Bim BH3 is a biological active peptide. |
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