| Cat.No. | Name | Information |
|---|---|---|
| M1883 | Ubenimex | Ubenimex, also known as bestatin, is a competitive protease inhibitor. |
| M55690 | L-Leucinol | L-Leucinol ((+)-Leucinol) is a potent, competitive leucine aminopeptidase inhibitor with Ki value of 17 μM. |
| M54833 | LYS006 hydrochloride | LYS-006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with IC50 of 2 nM. LYS-006 hydrochloride can be used for the research of inflammatory and autoimmune disorders, including ulcerative colitis and NASH. |
| M31118 | Gemtuzumab Ozogamicin | Gentuzumab ozogamicin is a human IgG4 CD33 monoclonal antibody (hP67.6) coupled to calicheamicin derivative, which can be used in studies related to CD33-positive AML. |
| M21495 | Firibastat | Firibastat (QGC001) is an orally active EC33 precursor drug. Firibastat is A first-in-class (first-in-class) brain aminopeptidase A (APA) inhibitor (Ki=200 nM) that selectively and specifically inhibits the conversion of cerebral angiotensin II to angiotensin III and lowers blood pressure in hypertensive rats. |
| M21111 | LYS-006 | LYS-006 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with IC50 of 2 nM. LYS-006 can be used for the research of inflammatory and autoimmune disorders, including ulcerative colitis and NASH. |
| M14298 | Bestatin hydrochloride | Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research. |
| M10560 | TNP-470 | TNP-470 (AGM-1470; NSC 642492) is a synthetic analog of fumagillin (or Fumagillol) and a methionine aminopeptidase-2 inhibitor. |
| M7549 | Acebilustat | Acebilustat is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory drug. |
| M2284 | Tosedostat | CHR-2797 is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively. |
| M52697 | Aminopeptidase N Ligand (CD13) NGR peptide | Aminopeptidase N Ligand (CD13) NGR peptide is a polypeptide targeting CD13 and can be used as a carrier to mediate intracellular transmission. |
| M52696 | H-D-Ala-D-Ala-D-Ala-D-Ala-OH | H-D-Ala-D-Ala-D-Ala-D-Ala-OH is a substrate for D-aminopeptidase. |
| M52695 | H-Leu-Trp-Met-Arg-OH | H-Leu-Trp-Met-Arg-OH is a tetrapeptide. |
| M52694 | NGR peptide | NGR peptide containing the Asn-Gly-Arg (NGR) motif. |
| M44790 | Batatasin IV | Batatasin IV is an LTA4H inhibitor with anti-inflammatory activity. |
| M31119 | IMGN-779 | IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML |
| M30487 | ARM1 | ARM1 (4BSA) is a potent aminopeptidase and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC50 7.61 µM and epoxide hydrolase inhibitory activity with an IC50 12.4 µM. |
| M28206 | Actinonin | Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities. |
| M27624 | Amastatin hydrochloride | Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with Ki values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase. |
| M25368 | Vixtimotamab | Vixtimotamab (AMV-564; TandAb T564) is a bispecific tetravalent tandem diabody (TandAb) that targets human CD33 and human CD3 antigens. Vixtimotamab can be used for the research of acute myeloid leukemia (AML). |
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