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Aminopeptidase Aminopeptidase

Cat.No.  Name Information
M1883 Ubenimex Ubenimex, also known as bestatin, is a competitive protease inhibitor.
M21495 Firibastat Firibastat (QGC001) is an orally active EC33 precursor drug. Firibastat is A first-in-class (first-in-class) brain aminopeptidase A (APA) inhibitor (Ki=200 nM) that selectively and specifically inhibits the conversion of cerebral angiotensin II to angiotensin III and lowers blood pressure in hypertensive rats.
M14298 Bestatin hydrochloride Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.
M10560 TNP-470 TNP-470 (AGM-1470; NSC 642492) is a synthetic analog of fumagillin (or Fumagillol) and a methionine aminopeptidase-2 inhibitor.
M7549 Acebilustat Acebilustat is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory drug.
M2284 Tosedostat CHR-2797 is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively.
M52697 Aminopeptidase N Ligand (CD13) NGR peptide Aminopeptidase N Ligand (CD13) NGR peptide is a polypeptide targeting CD13 and can be used as a carrier to mediate intracellular transmission.
M52696 H-D-Ala-D-Ala-D-Ala-D-Ala-OH H-D-Ala-D-Ala-D-Ala-D-Ala-OH is a substrate for D-aminopeptidase.
M52695 H-Leu-Trp-Met-Arg-OH H-Leu-Trp-Met-Arg-OH is a tetrapeptide.
M52694 NGR peptide NGR peptide containing the Asn-Gly-Arg (NGR) motif.
M44790 Batatasin IV Batatasin IV is an LTA4H inhibitor with anti-inflammatory activity.
M31119 IMGN-779 IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML
M31118 Gemtuzumab Ozogamicin Gentuzumab ozogamicin is a human IgG4 CD33 monoclonal antibody (hP67.6) coupled to calicheamicin derivative, which can be used in studies related to CD33-positive AML.
M30487 ARM1 ARM1 (4BSA) is a potent aminopeptidase and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC50 7.61 µM and epoxide hydrolase inhibitory activity with an IC50 12.4 µM.
M28206 Actinonin Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities.
M27624 Amastatin hydrochloride Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with Ki values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase.
M25368 Vixtimotamab Vixtimotamab (AMV-564; TandAb T564) is a bispecific tetravalent tandem diabody (TandAb) that targets human CD33 and human CD3 antigens. Vixtimotamab can be used for the research of acute myeloid leukemia (AML).
M21111 LTA4H-IN-1 LTA4H metalloenzyme inhibitor LYS006 is a selective oral agent in multiple Ph.II studies for the study of inflammatory diseases, including ulcerative colitis and NASH.




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