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ALDH Aldehyde Dehydrogenase

Cat.No.  Name Information
M6423 Alda-1 Alda-1 is a potent and selective Aldehyde Dehydrogenase-2 Agonist. Alda-1 activates wild-type ALDH2 and restores near wild-type activity to ALDH2*2.
M3706 CVT-10216 CVT-10216 is a highly selective, reversible inhibitor of ALDH-2 that reduces excessive alcohol drinking.
M58106 NCT-505 NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM. NCT-505 weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57, 22.8, 20.1, >57 μM, respectively.
M31093 RV01 RV01 is a novel quinolyl-substituted analogue of resveratrol, it inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol. RV01 exhibits hydroxyl radical scavenging activity.
M16813 Prunetin Prunetin is an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide.
M14296 4-Hydroxynonenal 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker.
M8781 NCT-501 NCT-501 is a potent and selective inhibitor of Aldehyde dehydrogenase ALDH1A1, a dehydrogenase that has been found to be elevated in certain cancers and in cancer stem cells.
M7487 WIN 18446 WIN 18446 is a aLDH1a2 inhibitor, with IC50 of 0.3 μM.
M1516 4-Diethylaminobenzaldehyde 4-Diethylaminobenzaldehyde
M29800 IGUANA-1  IGUANA-1 is a potent inhibitor of ALDH1B1, which is a mitochondrial enzyme that promotes colorectal and pancreatic cancer. IGUANA-1 has significant inhibition against cancer cells.
M29799 IGUANA-1 free base IGUANA-1 free base (STL5-T-0057) is an selective ALDH1 B1 inhibitor with an IC50 value of 30 nM. IGUANA-1 free base inhibits cell growth of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively. IGUANA-1 free base can be used for the research of cancer.
M29205 EN40  EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC50 value of 2 uM.
M20768 CM10 CM10 is a potent and selective inhibitor of aldehyde dehydrogenase 1A family (ALDH1A) with IC50 of 1700 nM, 740 nM and 640 nM for ALDH1A1, ALDH1A2 and ALDH1A3, respectively. CM10 exhibits anti-cancer activity.
M6384 A37 A37 is a aLDH1A1 inhibitor.




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