| Cat.No. | Name | Information |
|---|---|---|
| M17914 | Bellidifolin | Bellidifolin |
| M17903 | Gamma-Mangostin | Gamma-Mangostin (γ-Mangostin) is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities. |
| M17865 | Euphol | Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). |
| M17862 | Lupenone | Lupenone plays a role through the PI3K/Akt/mTOR and NF-κB signaling pathways. Lupenone has anti-inflammatory, antiviral, antidiabetic and anticancer activities. |
| M17858 | Niloticin | Niloticin is a osteoclastogenesis inhibitor. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways. Niloticin has anti-viral, antioxidative, and mosquitocidal activities. |
| M17844 | Lanosterol | Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases. |
| M17832 | β-Amyrin | β-Amyrin |
| M17808 | Hancolupenone | Hancolupenone is a natural product for research related to life sciences. |
| M17797 | Quillaic acid | Quillaic acid is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. Quillaic acid also has analgesic and local anti-inflammatory activity. |
| M17793 | 16-Oxoalisol A | 16-Oxoalisol A |
| M17784 | Oleanonic acid | Oleanonic acid (3-Oxooleanolic acid) is an orally available triterpene that has anti-inflammatory and insecticidal properties. In vitro, oleanonic acid can improve oxidative stress, autophagy defects, ferroptosis, mitochondrial damage, and endoplasmic reticulum stress induced by Amyloid-β, and in vivo, it can alleviate myocardial hypertrophy in rats. |
| M17770 | Pyracrenic acid | Pyracrenic acid |
| M17765 | Ginsenoside Rk3 | Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells. |
| M17749 | Ganodermanontriol | Ganodermanontriol is a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. |
| M17652 | Zeaxanthin dipalmitate | Zeaxanthin dipalmitate |
| M17651 | Tigogenin | Tigogenin |
| M17619 | 7-Oxo-β-sitosterol | 7-Oxo-β-sitosterol |
| M17603 | Cedrol | Cedrol is a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes. |
| M17591 | Heliangin | Heliangin |
| M17579 | Brevilin A | Brevilin A is an orally active STAT3/JAK inhibitor, with IC50 of 10.6 μM against STAT3. |
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