Cat.No. | Name | Information |
---|---|---|
M19040 | Bruceantinol | Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc. |
M19039 | Abietic acid | Abietic acid is an orally active diterpene isolated from Colophony. Abietic acid inhibits lipoxygenase activity for allergy. Abietic acid enhances cell migration and tube formation in HUVECs. Abietic acid induces significant angiogenic potential, which is associated with upregulation of extracellular signal-regulated kinase (ERK) and p38 expression. |
M19036 | L-Citrulline | L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway. |
M19035 | D-(+)-Fucose | D-(+)-Fucose prevents growth of Escherichia coli B/r on a mineral salts medium plus l-arabinose by inhibiting induction of the l-arabinose operon. D-fucose is a potent inducer of beta-methylgalactoside permease (MGP). |
M19008 | Regaloside C | Regaloside C |
M19003 | Taraxasterol | Taraxasterol is a pentacyclic triterpenoid compound isolated from Taraxacum mongolicum. Taraxasterol is an LXRα activator, with metabolic and anti-inflammatory effects. |
M18992 | Trigonelline | Trigonelline, an alkaloid with potential antidiabetic activity, is an efficient Nrf2 inhibitor capable of blocking Nrf2-dependent proteasome activity and thereby apoptosis protection in pancreatic cancer cells. |
M18988 | Picrocrocine | Picrocrocine |
M18976 | Piscidic acid | Piscidic acid |
M18964 | Nervonic Acid | Nervonic Acid is a monounsaturated fatty acid with oral activity. Nervonic acid exerts anti-inflammatory activity by inhibiting NF-κB signaling. |
M18961 | Cistanoside F | Cistanoside F is a phenylethanoid glycosid isolated from Cistanche deserticola, with antioxidative effect. |
M18959 | Norswertianin | Norswertianin |
M18952 | Cassiaside B2 | Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 is a 5-HT2C receptor agonist. Cassiaside B2 possesses antiallergic activity. |
M18932 | α-Spinasterol | α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively. |
M18925 | Dactylorhin A | Dactylorhin A is a succinate derivative ester isolated from rhizomes of Gymnadenia conopsea. Dactylorhin A exhibits moderate inhibitory effects on NO production effects in RAW 264.7 macrophage cells. |
M18924 | Strictosamide | Strictosamide has antiplasmodial and antifungal activities. Strictosamide can be used for the research of inflammation and inflammatory pain. |
M18910 | Octyl gallate | Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity. Octyl gallate (Progallin O) shows selective and sensitive fluorescent property. Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus. |
M18902 | Vanillic acid | Vanillic acid |
M18887 | Flavokawain C | Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells. |
M18886 | Oleandrigenin | Oleandrigenin is a metabolite and an Na(+)/K(+)-transporting ATPase inhibitor. Oleandrigenin is a steroid ester that is the 16-acetyl derivative of gitoxigenin. |
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