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Natural Products

Cat.No.  Name Information
M19388 Chicanin Chicanine is a lignan compound of Schisandra chinesis, inhibits LPS-induced phosphorylation of p38 MAPK, ERK 1/2 and IκB-α, with anti-inflammatory activity.
M19383 Aegeline Aegeline, a main alkaloid, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast. Aegeline restores growth of yeast cells suppressed by either αsyn or Bax. Antioxidant activity.
M19382 Sinigrin Sinigrin is a major glucosinolate present in plants of the Brassicaceae family, with anti-adipogenic effects.
M19381 Guaiacin Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation.
M19374 L-Rhamnose monohydrate L-Rhamnose monohydrate is a deoxy sugar found in plants and bacteria. Rhamnose monohydrate crosses the epithelia via the transcellular pathway and acts as a marker of intestinal absorption.
M19371 Handelin Handelin is a guaianolide dimer from Chrysanthemum boreale that has potent anti-inflammatory activity by down-regulating NF-κB signaling and pro-inflammatory cytokine production.
M19369 Geraniol Geraniol, an olefinic terpene, was found to inhibit growth of Candida albicans and Saccharomyces cerevisiae strains.
M19368 Osthenol Osthenol (Ostenol) is a selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B.
M19366 Karanjin Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis.
M19363 Parishin Parishin is a phenolic glucoside isolated from Gastrodia elata. Parishin exhibits antiaging effects and extends the lifespan of yeast via regulation of Sir2/Uth1/TOR signaling pathway.
M19361 Rosmanol Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect.
M19358 MONASCIN Monascin inhibits the activation of NOR 1 (an NO donor). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration.
M19356 Columbin Columbin is an orally active diterpenoid furanolactone from Calumbae radix, has anti-inflammatory and anti-trypanosomal effects. Columbin selectively inhibits COX-2 (EC50=53.1 μM) over COX-1 (EC50=327 μM).
M19354 Cytosine Cytosine is one of the four major bases found in DNA and RNA. cytosine modifications exhibit circadian oscillations associated with epigenetic diversity and aging.
M19353 Fraxinol Fraxinol is isolated from Lobelia chinensis.
M19351 Catenarin Catenarin
M19349 Hinokinin Hinokinin (Cubebinolide) is a compound isolated from the stems of Hypoestes aristate. Hinokinin exhibits moderate activity of HIV-1 protease enzyme.
M19347 Nimbolide Nimbolide induces apoptosis through inactivation of NF-κB. Nimbolide inhibits CDK4/CDK6 kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways.
M19344 Charantin Charantin
M19332 Licraside Licraside is isolated from Glycyrrhiza uralesis Fish.

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