All AbMole products are for research use only, cannot be used for human consumption.
Dexrazoxane hydrochloride is a cardioprotective agent. It inhibits DNA topoisomerase II (Topo II) without inducing DNA strand breaks. Dexrazoxane decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway.
| Molecular Weight | 304.73 |
| Formula | C11H16N4O4.HCl |
| CAS Number | 149003-01-0 |
| Solubility (25°C) | DMSO 60 mg/mL Water 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Topoisomerase Products |
|---|
| XR11576
XR11576 (MLN576) is an orally active inhibitor of topoisomerase I and II. |
| Silatecan
Silatecan (AR-67; DB 67) is a Camptothecin analogue with improved stability and lipophilicity. |
| 9-Hydroxyellipticine hydrochloride
9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. |
| Moxifloxacin-d4
Moxifloxacin-d4 |
| F14512
F14512 is a polyamine-containing inhibitor of DNA topoisomerase II with a broad spectrum of antitumor activities. |
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