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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M9776 | Darbufelone | Darbufelone is a dual inhibitor of cellular PGF2α and LTB4 production, it is also a COX-2 inhibitor potentially for the treatment of rheumatoid arthritis. |
| M9473 | RO1138452 | RO1138452 is a potent and selective antagonist for both human and rat IP receptors and that is possesses analgesic and anti-inflammatory potential. |
| M9464 | Asapiprant | Asapiprant is a potent and selective DP1 receptor antagonist, with a Ki of 0.44 nM. |
| M9446 | Dazoxiben hydrochloride | Dazoxiben hydrochloride is a potent, orally active thromboxane (TX) synthase inhibitor that reduces the formation of blood clots. |
| M9277 | TG4-155 | TG4-155 is a brain penetrant prostaglandin EP2 specific antagonist, with a Ki of 9.9 nM. |
| M9232 | PF-04418948 | PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. |
| M8973 | Fevipiprant | Fevipiprant (QAW039) is a selective, potent, reversible competitive CRTh2 antagonist. |
| M8971 | Grapiprant | Grapiprant is a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. |
| M6138 | E-7046 | E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities. |
| M5929 | Prostaglandin E2 | Prostaglandin E2 is a vasodilator isolated from prostate gland secretion, working by binding and activating the prostaglandin E2 receptor. |
| M5401 | Alprostadil | Alprostadil is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist. |
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