| Cat.No. | Name | Information |
|---|---|---|
| M5929 | Prostaglandin E2 | Prostaglandin E2 is a vasodilator isolated from prostate gland secretion, working by binding and activating the prostaglandin E2 receptor. |
| M5401 | Prostaglandin E1 (Alprostadil) | Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, which induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases. |
| M58562 | Prostaglandin D2 | Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals. PGD2 plays a protective role by suppressing inflammation. |
| M54771 | Carbacyclin | Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation. |
| M43605 | 15-keto-Prostaglandin E2 | 15-keto-Prostaglandin E2 is an endogenous metabolite. |
| M31219 | CAY10580 | CAY10580 is a potent and selective prostaglandin EP4 receptor agonist (Ki=35 nM). |
| M30662 | Treprostinil diethanolamine | Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (UT-15C) diethanolamine increases upregulation of cAMP toward maintaining homeostasis within the vasculature. Treprostinil (UT-15C) diethanolamine can result in vasodilatation of human pulmonary arteries. |
| M30400 | L-902688 | L-902688 is a potent, selective and orally active EP4 receptor agonist with a Ki of 0.38 nM and an EC50 of 0.6 nM. L-902688 shows >4,000-fold selective for EP4 over other EP and prostanoid receptors. |
| M30068 | Latanoprost acid | Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes. |
| M20978 | Treprostinil sodium | Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a stabilized tricyclic analog of prostacyclin and a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively. Treprostinil promotes vasodilation and inhibits platelet aggregation in pulmonary and systemic arterial vascular beds, and can be used in studies related to pulmonary arterial hypertension (PAH). |
| M20392 | Bimatoprost | Bimatoprost is a synthetic prostaglandin analog as well as a prostaglandin F (FP) receptor agonist (FPA) with IOP-lowering activity for studies related to glaucoma and IOP. |
| M14045 | Selexipag | Selexipag (NS-304) is the methanesulfonamide precursor compound of ACT-333679 and an orally effective prostacyclin (PGI2) receptor agonist. It can be used in studies related to pulmonary arterial hypertension. |
| M10858 | MK-2894 | MK-2894 is a potent, selective, orally active and high affinity (Ki=0.56 nM) full antagonist against E prostanoid receptor 4 (EP4 receptor) (IC50=2.5 nM). MK-2894 possesses potent anti-inflammatory activity in animal models of pain/inflammation and can be used for the research of arthritis. |
| M10803 | Butaprost | Butaprost is a selective prostaglandin E receptor (EP2) agonist for murine EP2 receptors EC50 The value is 33 nM,Ki The value is 2.4 μM. Butaprost is less active against rodents EP1, EP3 and EP4 receptors. Butaprost mitigates fibrosis by obstructing TGF-β/Smad2 signaling. |
| M10680 | AH 6809 | AH 6809 is an antagonist of EP and DP receptors against cloned humans EP1，EP2，EP3-III and DP receptors Ki Values were 1217, 1150, 1597, and 1415 nM, respectively, for mice EP2 receptors Ki The value is 350 nM. |
| M10679 | Evatanepag | Evatanepag (CP-533536 free acid) is a potent selective EP2 receptor agonist with an IC50 of 50 nM for rEP2. |
| M10632 | AM211 | AM-211 is a novel and potent antagonist of the prostaglandin D2 receptor type 2, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively. |
| M10579 | Dinoprost tromethamine | Dinoprost tromethamine (Prostaglandin F2α tromethamine) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. |
| M10481 | Omidenepag | Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. |
| M10270 | Agnuside | Agnuside is a compound isolated from Vitex negundo with anti-arthritic activity. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
