Cat.No. | Name | Information |
---|---|---|
M5929 | Prostaglandin E2 | Prostaglandin E2 is a vasodilator isolated from prostate gland secretion, working by binding and activating the prostaglandin E2 receptor. |
M9776 | Darbufelone | Darbufelone is a dual inhibitor of cellular PGF2α and LTB4 production, it is also a COX-2 inhibitor potentially for the treatment of rheumatoid arthritis. |
M9473 | RO1138452 | RO1138452 is a potent and selective antagonist for both human and rat IP receptors and that is possesses analgesic and anti-inflammatory potential. |
M9464 | Asapiprant | Asapiprant is a potent and selective DP1 receptor antagonist, with a Ki of 0.44 nM. |
M9446 | Dazoxiben hydrochloride | Dazoxiben hydrochloride is a potent, orally active thromboxane (TX) synthase inhibitor that reduces the formation of blood clots. |
M9277 | TG4-155 | TG4-155 is a brain penetrant prostaglandin EP2 specific antagonist, with a Ki of 9.9 nM. |
M9232 | PF-04418948 | PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. |
M8973 | Fevipiprant | Fevipiprant (QAW039) is a selective, potent, reversible competitive CRTh2 antagonist. |
M8971 | Grapiprant | Grapiprant is a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. |
M8780 | ONO-AE3-208 | ONO-AE3-208 is an orally active prostaglandin E2 receptor 4 (EP4)-selective antagonist (Ki in nM = 1. |
M7428 | Treprostinil | Treprostinil (UT-15) is a potent prostacyclin (PGI 2) analog. |
M7426 | Travoprost | Travoprost is a potent and selective FP prostaglandin receptor agonist. |
M7385 | TCS 2510 | TCS 2510 is a selective EP4 agonist. |
M6714 | Epoprostenol sodium | Epoprostenol is an endogenous steroid and a selective agonist of the prostaglandin I2 receptor (PI2R) that inhibits platelet aggregation and induces vasodilation. It can be used in studies related to pulmonary hypertension. |
M6138 | E-7046 | E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities. |
M5955 | Seratrodast | Seratrodast(AA 2414) is a potent and selective thromboxane A2 receptor (TP) antagonist. |
M5918 | Ramatroban | Ramatroban (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. |
M5846 | Ozagrel HCl | Ozagrel HCl is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. |
M5729 | Latanoprost | Latanoprost is a prostaglandin F2α analog as well as a prostaglandin-like selective FP receptor agonist with lipophilic and corneal penetrating properties. In addition, Latanoprost also increases ocular fluid outflow, thereby reducing intraocular pressure, and may be used in studies related to glaucoma. |
M5401 | Prostaglandin E1 (Alprostadil) | Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, which induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases. |
M3951 | Terutroban | Terutroban is a selective antagonist of the thromboxane receptor. |
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