| Cat.No. | Name | Information |
|---|---|---|
| M5929 | Prostaglandin E2 | Prostaglandin E2 is a vasodilator isolated from prostate gland secretion, working by binding and activating the prostaglandin E2 receptor. |
| M3881 | Tafluprost | Tafluprost is a fluorinated analog of prostaglandin F2-alpha and a PGF2alpha agonist that may be used in glaucoma-related studies. |
| M2689 | Ethamsylate | Ethamsylate is a haemostatic compound, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion. |
| M50157 | DT-9081 | DT-9081 is a potentially best-in-class, orally active, small molecule prostaglandin EP4 receptor antagonist that reverses prostaglandin E2 (PGE2)-induced immunosuppression in certain tumors by blocking the EP4 receptor present on immune cells. |
| M43878 | Unoprostone | Unoprostone is a prostaglandin F2α analog (PGAs) that reduces oxidative stress and light-induced retinal cell death as well as phagocytosis dysfunction by activating BK channels. It can be used in studies related to glaucoma or hypertension. |
| M43605 | 15-keto-Prostaglandin E2 | 15-keto-Prostaglandin E2 is an endogenous metabolite. |
| M41911 | Prostaglandin B1 | Prostaglandin B1 (PGB1) is a metabolite of Prostaglandin E1. |
| M41910 | EP3 antagonist 4 | EP3 antagonist 4 is an EP3 antagonist, with a Ki value of 2 nM for hEP. |
| M41909 | Vorbipiprant | Vorbipiprant (CR6086) is an EP4 receptor antagonist, serving as a targeted immunomodulator. |
| M41908 | AMX12006 | AMX12006 is a potent, selective and orally active EP4 antagonist with an IC50 value of 4.3 nM. |
| M41907 | FR181157 | FR181157, an orally active PGI2 agonist activity with especially good pharmacokinetic properties. |
| M41906 | PDC31 | PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor. |
| M41905 | BAY-6672 hydrochloride | BAY-6672 hydrochloride is a potent and selective human Prostaglandin F (FP) receptor antagonist with an IC50 value of 11 nM. |
| M38968 | (-)-Curine | (-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated from Chondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition of prostaglandin E2 production. |
| M38967 | Thielavin B | Thielavin B is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin B effectively influences the prostaglandin E2 synthesis from the endoperoxide. Thielavin B is significantly effective on carrageenan-induced oedema of rats when administered intravenously. |
| M38966 | Saikogenin D | Saikogenin D activates epoxygenases that converts arachidonic acid to epoxyeicosanoids and dihydroxyeicosatrienoic acids, and the metabolites secondarily inhibit prostaglandin E2 (PGE2) production. Saikogenin D results in an elevation of [Ca2+]i due to Ca2+ release from intracellular stores. |
| M31221 | Laropiprant sodium | Laropiprant sodium is a potent and selective DP receptor antagonist with Ki values of 0.57 nM and 2.95 nM for DP receptor and TP Receptor, respectively. |
| M31220 | I-SAP | I-SAP is a radioiodinated TXA2/PGH2 receptor antagonist. The bind between I-SAP and the receptors, is inhibited by the histidine modifying reagent diethyl-pyrocarbonate (DEPC). |
| M31037 | ONO-8711 dicyclohexylamine | ONO-8711 dicyclohexylamine is a selective and orally active EP1 competitive antagonist with Ki value of 0.6 nM and 1.7 nM for human and mouse EP1 respectively. ONO-8711 dicyclohexylamine effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer. |
| M30809 | PGD2-IN-1 | PGD2-IN-1 is an antagonist of DP, with an IC50 of 0.3 nM. |
| M30780 | Amtolmetin guacil | Amtolmetin guacil is an effective nonsteroidal anti-Inflammatory agent with pain-relieving effects. Amtolmetin guacil inhibits prostaglandin synthesis and cyclooxygenase (COX). Amtolmetin guacil can stimulate capsaicin receptors present on the gastrointestinal wall and also releases gastroprotective nitric oxide (NO). Amtolmetin guacil can be used to research knee osteoarthritis. |
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