Catalog

Potassium Channel Potassium channel

Inhibitors

Cat.No.	Name	Information
M9423	CLP290	CLP290 is a novel, orally available KCC2 modulator, highly selective for KCC2 over related Cl- transporters.
M9394	BMS-191011	BMS-191011 is a potent BK_Ca channel opener (large-conductance Ca²⁺-activated potassium channel, K_Ca1.1).
M7926	Minoxidil	Minoxidil activates ATP-activated K⁺ channels; vasodilator; slow or stop hair loss and promote hair regrowth.
M6052	Vernakalant HCl	Vernakalant Hcl(RSD-1235) is an investigational mixed ion channel blocker that can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents; in treatment of antiarrhythmic.
M5728	Lansoprazole	Lansoprazole is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid.
M5569	Diazoxide	Diazoxide is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions.
M5437	Azimilide	Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.
M5409	Amiodarone	Amiodarone HCl is a sodium/potassium-ATPase inhibitor and an autophagy activator, used to treat various types of cardiac dysrhythmias.
M5302	ICA069673	ICA-069673 is a KCNQ2/Q3 potassium channel activator with an IC50 of 0.69 μM.
M4584	Acacetin	Acacetin is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects.
M3714	Repaglinide	Repaglinide is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes.
M3622	Vernakalant	Vernakalant (RSD-1235) is an investigational mixed ion channel blocker, which can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents.
M3456	Chlorpromazine hydrochloride	Chlorpromazine hydrochloride is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 μM for nward-rectifying K+ currents and time-independent outward currents
M3415	Nateglinide	Nateglinide is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.
M3399	Gliclazide	Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM.
M3343	Nicorandil	Nicorandil is potassium channel activator.
M3192	TRAM-34	TRAM-34 is a selective and potent inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1) with K_d of 20 nM, 200- to 1500-fold selective over other ion channels, and does not block cytochrome P450.
M3077	Tolbutamide	Tolbutamide is an inhibitor of cAMP with IC50 of 4 mM.
M2724	Gliquidone	Gliquidone is an ATP-sensitive K⁺ channel antagonist with IC50 of 27.2 nM.
M2181	ML133 hydrochloride	ML133 hydrochloride is a selective inhibitor of the Kir2 family of inward rectifier (IRK, KCNJ) potassium channels.
M2043	TAK-438	TAK-438 is a novel and potent potassium-competitive acid blocker (P-CAB) with IC50 of 19 nM.
M1797	Retigabine	Retigabine is a KCNQ/Kv7 potassium channel activator which functions by enhancing potassium currents via stabilizing the open conformation of the Kv7.2-7.3 channels.

Signaling Pathways

Product Type

Potassium Channel Potassium channel

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