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Potassium Channel Potassium channel

Inhibitors

Cat.No.  Name Information
M11045 OR-1896 Or-1896 is an active longevity metabolite of Levosimendan. Or-1896, a highly selective phosphodiesterase (PDE III) inhibitor, is a powerful vasodilator.
M10624 Tetraethylammonium chloride Tetraethylammonium chloride is a non-selective potassium channel blocker with antitumor properties.
M10575 Charybdotoxin TFA Charybdotoxin TFA, a 37-amino acid peptide, is a K+ channel blocker.
M10516 AUT1 AUT1 is a Kv3 potassium channel modulator which increases whole currents mediated by human Kv3.1b and Kv3.2a channels, with a concomitant leftward shift in the voltage-dependence of activation, while having a less potent effect on hKv3.3 currents.
M9820 2,2,2-Trichloroethanol 2,2,2-Trichloroethanol is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4).
M9780 Nigericin Nigericin is an antibiotic derived from Streptomyces hygroscopicus, it acts as an H+, K+, Pb2+ ionophore.
M9700 ML213 ML213 (CID-3111211) is a selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener, with EC50 values of 230 and 510 nM for KV7.2 and KV7.4, respectively.
M9423 CLP290 CLP290 is a novel, orally available KCC2 modulator, highly selective for KCC2 over related Cl- transporters.
M9394 BMS-191011 BMS-191011 is a potent BKCa channel opener (large-conductance Ca2+-activated potassium channel, KCa1.1).
M7926 Minoxidil Minoxidil activates ATP-activated K+ channels; vasodilator; slow or stop hair loss and promote hair regrowth.
M7029 Nigericin sodium salt Nigericin (NSC 292567) sodium salt is a selective K+ ionophore, Nigericin sodium salt is also an NLRP3 activator which can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes.
M6975 ML297 ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator.
M6908 Linopirdine dihydrochloride Linopirdine dihydrochloride is a Kv7 (KCNQ) channel blocker.
M6052 Vernakalant HCl Vernakalant Hcl(RSD-1235) is an investigational mixed ion channel blocker that can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents; in treatment of antiarrhythmic.
M5728 Lansoprazole Lansoprazole is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid.
M5569 Diazoxide Diazoxide is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions.
M5437 Azimilide Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.
M5409 Amiodarone Amiodarone HCl is a sodium/potassium-ATPase inhibitor and an autophagy activator, used to treat various types of cardiac dysrhythmias.
M5368 4-Aminopyridine 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
M5302 ICA069673 ICA-069673 is a KCNQ2/Q3 potassium channel activator with an IC50 of 0.69 μM.



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