| Cat.No. | Name | Information |
|---|---|---|
| M4973 | BAPTA-AM | BAPTA-AM is a selective, membrane-permeable calcium chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively. |
| M2181 | ML133 hydrochloride | ML133 hydrochloride is a selective inhibitor of the Kir2 family of inward rectifier (IRK, KCNJ) potassium channels. |
| M3456 | Chlorpromazine hydrochloride | Chlorpromazine hydrochloride is an antagonist of D2, 5HT2A, potassium and sodium channels. The Ki of Chlorpromazine Hydrochloride to D2 and 5HT2A were 363 nM and 8.3 nM, respectively. Chlorpromazine also excites the 20S proteasome. *The compound is unstable in solutions, freshly prepared is recommended |
| M7029 | Nigericin sodium salt | Nigericin (NSC 292567) sodium salt is a selective K+ ionophore, Nigericin sodium salt is also an NLRP3 activator which can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes. |
| M5569 | Diazoxide | Diazoxide is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions. |
| M5437 | Azimilide | Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes. |
| M5409 | Amiodarone hydrochloride | Amiodarone HCl is a sodium/potassium-ATPase inhibitor and an autophagy activator, used to treat various types of cardiac dysrhythmias. |
| M5406 | Amifampridine | Amifampridine is a drug, predominantly in the treatment of a number of rare muscle diseases. |
| M5302 | ICA069673 | ICA-069673 is a KCNQ2/Q3 potassium channel activator with an IC50 of 0.69 μM. |
| M5072 | NS-1619 | NS-1619 is a selective large conductance Ca2+-activated K+-channel activator. |
| M4968 | Mitiglinide calcium hydrate | Miglinide calcium hydrate is a compound used to study type 2 diabetes mellitus. It is a highly selective KATP channel antagonist. |
| M4891 | Ns6180 | NS6180 is a highly selective inhibitor of KCa3.1 ion channels with an IC50 value of 9nM, blocking T cell activation and inflammatory response. |
| M4584 | Acacetin | Acacetin is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects. |
| M4332 | Paederosidic-acid-methyl-ester | Paederosidic acid Methyl ester, an ATP-sensitive K+ Channel activator, was isolated from P. scandens. Paederosidic acid Methyl ester has shown significant central pain-relieving activity, increasing pain thresholds by activating ATP-sensitive K+ channels in the brain and spinal cord levels. |
| M4160 | Soyasaponin-Be | Dehydrosoyasaponin I (Soyasaponin Be; Dhs-i, a triterpenoid glycoside, is a potent and reversible calcium-activated potassium (MAxi-K) channel activator. |
| M4031 | Talatisamine | Talatisamine isa kind of aconite alkaloid, which isa specific K+ channel blocker. Talatisamine attenuated the neurotoxicity of beta-amyloid oligomers to cultured cortical neurons. |
| M3957 | Mitiglinide calcium | Mitiglinide (KAD 1229, S 21403), a derivative of benzysuccinic acid, is a potassium channel antagonist developed with Kissei for the study of type 2 diabetes. |
| M3718 | Dronedarone hydrochloride | Donedarone hydrochloride is a new compound with a similar structure to amiodarone and has better side effects. |
| M3714 | Repaglinide | Repaglinide is an insulin secretagogue used in type 2 diabetes. |
| M3622 | Vernakalant | Vernakalant (RSD-1235) is an investigational mixed ion channel blocker, which can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents. |
| M3505 | Glipizide | Glipizide is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes. |
| M3464 | Indapamide | Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure. |
| M3452 | Quinine hydrochloride Dihydrate | Quinine hydrochloride Dihydrate is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste. |
| M3449 | PF-3716556 | PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+ |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
