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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M5650 | Fluconazole | Fluconazole is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections. |
| M5059 | Furafylline | Furafylline was a potent, non-competitive inhibitor of high affinity phenacetin O-deethylase activity of microsomal fractions of human liver, a reaction catalysed by P450IA2, with an IC50 value of 0.07 microM. |
| M4146 | Sodium-Danshensu | Sodium-Danshensu |
| M4000 | Naringenin | Naringenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess strong anti-proliferative properties and the ability to induce apoptosis in hepatoma cell lines. |
| M3953 | Voriconazole | Voriconazole is an inhibitor of 14α-lanosterol demethylase with IC50 value of 53nM. |
| M3708 | Anastrozole | Anastrozole is a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis. |
| M3591 | Abiraterone Acetate | Abiraterone Acetate is an acetate salt form of Abiraterone which is a steroidal cytochrome CYP17 inhibitor with IC50 of 72 nM. |
| M3326 | Memantine hydrochloride | Memantine hydrochloride is a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively. |
| M2058 | Ketoconazole | Ketoconazole is a potent inhibitor of cytochrome P450c17. |
| M1839 | MDV3100 | MDV3100 is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. |
| M1814 | Avasimibe | Avasimibe (CI-1011) is a novel orally bioavailable ACAT inhibitor with IC50 values of 2.9, 13.9, 26.5 µM for CYP2C9, CYP1A2 and CYP2C19, respectively. |
| M1636 | Abiraterone | Abiraterone acetate (CB-7598) is a potent, selective, and orally available inhibitor of CYP17 with an IC50 of 4 nM. |
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