Cat.No. | Name | Information |
---|---|---|
M3326 | Memantine hydrochloride | Memantine hydrochloride is a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively. |
M2079 | Chrysin | Chrysin is a naturally occurring flavone chemically extracted from the passion flowers Passiflora caerulea. |
M1636 | Abiraterone | Abiraterone acetate (CB-7598) is a potent, selective, and orally available inhibitor of CYP17 with an IC50 of 4 nM. |
M52647 | Cytochrome P450 reductase | Cytochrome P450 reductase is a NADPH-cytochrome reductase. |
M45355 | 20-SOLA | 20-SOLA is a water-soluble 20-HETE antagonist. |
M45354 | TS-011 | TS-011 is a selective inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis. |
M45353 | Dibromo-dodecenyl-methylsulfimide | Dibromo-dodecenyl-methylsulfimide is a selective inhibitor of 20-HETE synthesis and attenuates the vasodilatory response to sodium nitroprusside (SNP). |
M45022 | Terpinyl acetate | α-Terpinyl acetate is a monoterpene ester isolated from Laurus nobilis L. |
M44872 | Harmidol hydrochloride | Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. |
M44743 | 4'-Methylchrysoeriol | 4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. |
M44695 | 2',5,6',7-Tetrahydroxyflavone | 5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM. |
M42318 | ONT-993 | ONT-993 is an aliphatic hydroxylated metabolite. |
M42317 | CAY 10434 | CAY 10434 is a potent CYP4A hydroxylase inhibitor. |
M42316 | Erysolin | Erysolin is a CYP1A inhibitor with antigenic toxicity. |
M42315 | hCYP3A4-IN-1 | hCYP3A4-IN-1 is a potent, orally active hCYP3A4 inhibitor. |
M42314 | SU 10603 | SU 10603 is a specific inhibitor of P45017α (P450c17; CYP17A1). |
M42313 | CAY 10462 dihydrochloride | CAY 10434 dihydrochloride is a potent CYP4A hydroxylase inhibitor. |
M42312 | CYP11A1-IN-1 | CYP11A1-IN-1 is an inhibitor of CYP11A1, with IC50 value of 201-2000 nM. |
M42310 | hCYP3A4 Fluorogenic substrate 1 | hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an Km value of 0.36 μM. |
M42309 | hCYP1B1-IN-1 | hCYP1B1-IN-1 is a hCYP1B1 inhibitor (IC50=3.6 nM), as well as an antagonist of Aryl Hydrocarbon Receptor. |
M39062 | Kushenol M | Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC50 values of 1.29 μM for CYP3A4 in human liver microsomes. |
M39059 | Isoglycycoumarin | Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6). |
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