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Cytochrome P450 (e.g. CYP17) Cytochrome P450 (e.g. CYP17)

Cat.No.  Name Information
M3326 Memantine hydrochloride Memantine hydrochloride is a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively.
M2079 Chrysin Chrysin is a naturally occurring flavone chemically extracted from the passion flowers Passiflora caerulea.
M1636 Abiraterone Abiraterone acetate (CB-7598) is a potent, selective, and orally available inhibitor of CYP17 with an IC50 of 4 nM.
M52647 Cytochrome P450 reductase Cytochrome P450 reductase is a NADPH-cytochrome reductase.
M45355 20-SOLA 20-SOLA is a water-soluble 20-HETE antagonist.
M45354 TS-011 TS-011 is a selective inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis.
M45353 Dibromo-dodecenyl-methylsulfimide Dibromo-dodecenyl-methylsulfimide is a selective inhibitor of 20-HETE synthesis and attenuates the vasodilatory response to sodium nitroprusside (SNP).
M45022 Terpinyl acetate α-Terpinyl acetate is a monoterpene ester isolated from Laurus nobilis L.
M44872 Harmidol hydrochloride Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala.
M44743 4'-Methylchrysoeriol 4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD.
M44695 2',5,6',7-Tetrahydroxyflavone 5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM.
M42318 ONT-993 ONT-993 is an aliphatic hydroxylated metabolite.
M42317 CAY 10434 CAY 10434 is a potent CYP4A hydroxylase inhibitor.
M42316 Erysolin Erysolin is a CYP1A inhibitor with antigenic toxicity.
M42315 hCYP3A4-IN-1 hCYP3A4-IN-1 is a potent, orally active hCYP3A4 inhibitor.
M42314 SU 10603 SU 10603 is a specific inhibitor of P45017α (P450c17; CYP17A1).
M42313 CAY 10462 dihydrochloride CAY 10434 dihydrochloride is a potent CYP4A hydroxylase inhibitor.
M42312 CYP11A1-IN-1 CYP11A1-IN-1 is an inhibitor of CYP11A1, with IC50 value of 201-2000 nM.
M42310 hCYP3A4 Fluorogenic substrate 1 hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an Km value of 0.36 μM.
M42309 hCYP1B1-IN-1 hCYP1B1-IN-1 is a hCYP1B1 inhibitor (IC50=3.6 nM), as well as an antagonist of Aryl Hydrocarbon Receptor.
M39062 Kushenol M Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC50 values of 1.29 μM for CYP3A4 in human liver microsomes.
M39059 Isoglycycoumarin Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6).




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